辐射暴露的基因组效应:哺乳动物细胞中癌症和遗传畸变的诱导

Q4 Earth and Planetary Sciences Research Journal of Chemistry and Environment Pub Date : 2023-08-15 DOI:10.25303/2709rjce1120122
Pankaj Garg
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引用次数: 0

摘要

辐射暴露是一把双刃剑。一方面,放疗的部署是恶性肿瘤治疗中最可接受的方式之一,因为它能够杀死癌细胞。同样,人们害怕暴露在以核灾难的形式出现的人为排放物中,或者与战争期间任何形式的搞笑发电有关。在没有任何明显副作用的情况下,促进人体承受小强度的排放是合理的。然而,暴露在高水平的辐射中会产生无数有害的副作用。这些有害的副作用使公众在了解辐射照射的实际机制和具体补救措施时产生了潜在的恐惧。本研究详细探讨了辐射安全的原理,以及不同类型的辐射在不同强度下对人体的影响。此外,还讨论了细胞突变是如何在不同的器官和身体系统中由于不同水平的辐射暴露而产生的,以及生物体为抵消辐射的有害影响而产生耐药性(阈值限制)的潜力。
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The genomic effects of radiation exposure: induction of cancers and genetic aberrations in mammalian cells
Radiation exposure can be a two-edged sword. On one hand, the deployment of radiotherapy is one of the most acceptable modalities for malignancy treatment, for the reason of its ability to kill cancer cells. Equally, one is scared of the exposure to man-made emissions in the form of nuclear disasters or related to any form of hilarious power generation during the war. It is rational to facilitate the body enduring small intensity of emissions without any marked side effects. However, there are countless detrimental side effects of being exposed to elevated levels of radiation. These harmful side effects form an underlying fear in the general public in understanding the actual mechanism and concrete remediation of radiation exposure. The present study investigates in detail the principles of radiation safety and how different types of radiation emissions affect the human body when exposed at different levels of their intensity. Furthermore, it is also conferred how cellular mutations are originated in different organs and body systems due to different levels of radiation exposure and also the potential of organisms to develop resistance (threshold limit) to counteract harmful effects of radiation.
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来源期刊
CiteScore
0.50
自引率
0.00%
发文量
195
审稿时长
4-8 weeks
期刊介绍: Information not localized
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