回顾性分析吉尔吉斯斯坦比什凯克市国立医院收治的69例脑囊性包虫病患者

Q4 Biochemistry, Genetics and Molecular Biology Biomedicine (India) Pub Date : 2023-11-09 DOI:10.51248/.v43i5.3414
Keneshbek Yrysov, Taalaybek Seyitbekov, Nurlan Mamashev, Beksultan Yrysov, Jumabek Tashibekov
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引用次数: 0

摘要

简介和目的:囊性棘球蚴病(CE)是一种严重的、广泛存在的寄生虫病,在许多国家仍然是一个重大的健康问题。本研究的目的是了解臭氧盐溶液(O3SS)清除包虫囊肿的效果,以提高脑CE患者神经外科治疗的效果,并提出预防该病的建议。方法:本研究纳入69例在我院手术治疗的脑CE患者。该诊断在手术时得到确认,这使我们能够评估22例(31.9%)患者的计算机断层扫描和47例(68.1%)患者的磁共振成像数据。结果:69例患者均出现寄生性囊肿,术中确诊。采用Dowling-Orlando技术完整切除包虫囊肿43例(62.3%)。O3SS处理脑包虫病残留空腔的最佳暴露时间为10分钟。随访时间为8-18个月。结论:在O3SS浓度为10 ~ 15mg /l的条件下,生殖细胞超微结构发生不可逆变化,使其在5分钟内不能形成新的囊肿。
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Retrospective study of 69 cases of cerebral cystic echinococcosis in patients admitted to National hospital in Bishkek city, Kyrgyzstan
Introduction and Aim: Cystic echinococcosis (CE) is a severe, widespread parasitic sickness that continues to be a significant health concern in many countries. The goal of the study was to find out how well ozonized saline solution (O3SS) cleans hydatid cysts to improve the results of neurosurgical treatment for patients with cerebral CE and to make suggestions for preventing the disease. Methods: This study included 69 patients with cerebral CE who were operated in our hospital. The diagnosis was confirmed at the time of the surgery, which allowed us to evaluate the data of computerized tomography in 22 (31.9%) and magnetic resonance imaging in 47 (68.1%) patients of the brain. Results: All 69 examined patients presented with cysts of parasitic origin, which were confirmed intraoperatively. Intact removal of hydatid cysts using the Dowling-Orlando technique was performed in 43 cases (62.3%). The best exposure duration for processing residual cavities in brain echinococcosis utilizing O3SS is 10 minutes. The duration of the follow-up period ranged from 8–18 months. Conclusion: When larvocysts of CE are exposed to 10–15 mg/l of O3SS, the germ cells go through irreversible changes in their ultrastructure that stop them from making new cysts within five minutes.
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Biomedicine (India)
Biomedicine (India) Biochemistry, Genetics and Molecular Biology-Biochemistry, Genetics and Molecular Biology (all)
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