阿拉伯联合酋长国哈伊马角一家二级护理医院的儿科抗菌药物使用情况

Sarah Dawood, Yasmin Sharifian, Masah Mardini, Duaa Jawhar, Laxminarayana Kurady Bairy, Suresh Kumar Srinivasamurthy
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摘要

目的了解阿拉伯联合酋长国某二级医院儿科住院患者抗菌药物的使用情况。方法前瞻性研究基于从2020年9月至2021年7月11个月期间收集的600例患者的电子记录。主要患者人群为在阿拉伯联合酋长国哈伊马角(RAK) Saqr医院接受抗微生物药物治疗的儿科患者。收集的数据包括一般患者信息、实验室调查、诊断、慢性疾病和使用的抗菌素。根据世卫组织解剖治疗化学分类,计算每位患者对每种抗菌药物的规定每日剂量(DDDs)。结果在11个月的研究期间,在儿科住院的1400名患者中,600名(42.8%)接受了抗菌素治疗。平均住院时间为3.44天,每位患者平均每份处方使用1.41个抗菌剂。抗菌药物治疗的平均天数为6.9天。患者以0 ~ 5岁为主(61.1%),男性占总样本的58%。在所开的41种不同抗菌药中,使用频率最高的是-内酰胺共阿莫昔拉韦(J01CR02)(19.3%),其次是头孢呋辛(J01DC02)(16.3%)、阿莫西林(J01CA04)(15.0%)和阿奇霉素(J01FA10)(5.99%)。这些药物主要通过肠外途径给药,最常见的适应症是呼吸道疾病。结论:我们的研究得出结论,大多数儿科患者的处方抗菌素属于世卫组织可获取和观察组。共阿莫昔拉夫、头孢呋辛和阿莫西林是最常用的抗菌剂。使用的主要适应症是呼吸道疾病。
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Pediatric Antimicrobial Usage in a Secondary Care Hospital in Ras Al Khaimah, United Arab Emirates
Objective To assess the pattern of antimicrobial use among pediatric inpatients in a secondary care hospital in the United Arab Emirates. Methods The prospective study was conducted based on the electronic records of 600 patients, collected over a period of 11 months, from September 2020 to July 2021. The primary patient population was the pediatric patients receiving antimicrobials admitted to Saqr Hospital, Ras Al Khaimah (RAK), United Arab Emirates (UAE). The data gathered includes general patient information, lab investigations, diagnoses, chronic medical conditions, and antimicrobials used. The number of defined daily doses (DDDs) administered per patient was calculated for each antimicrobial prescribed as per the WHO anatomical therapeutic chemical classification. Results Out of 1400 patients admitted to the pediatric unit during the 11-month study period, 600 (42.8%) received antimicrobials. The mean duration of hospital stay was 3.44 days, and each patient received a mean of 1.41 antimicrobials per prescription. The mean days of antimicrobial therapy were 6.9 days. The majority of the patients were aged 0–5 years (61.1%), and 58% of the total sample was male. Amongst a total of 41 different antimicrobials prescribed, the beta-lactam co-amoxiclav (J01CR02) was the most frequently (19.3%) used one, followed by cefuroxime (J01DC02) (16.3%), amoxicillin (J01CA04) (15.0%), and azithromycin (J01FA10) (5.99%). These were administered mainly via the parenteral route, and the most common indication was respiratory disease. Conclusion Our study concludes that most of the prescribed antimicrobials for pediatric patients are within the WHO access and watch group. Co-amoxiclav, cefuroxime, and amoxicillin are the most frequently used antimicrobials. The main indication for use was respiratory illness.
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