犬静脉注射美洛昔康后过敏反应1例

IF 0.4 4区 农林科学 Q4 VETERINARY SCIENCES Arquivo Brasileiro De Medicina Veterinaria E Zootecnia Pub Date : 2023-10-01 DOI:10.1590/1678-4162-12961
S.L. Beier, M.P.A. Lima, R.A. Silva, O.H.R. Ladeira, E.H. Bitencourt, S.E.M.T. Branco, F.G. Sousa
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摘要

虽然在兽医学中很少报道,但本文报道了三例犬在静脉注射治疗剂量的美洛昔康后出现过敏反应的病例。本文对3只不同品种和年龄的犬进行了卵巢子宫切除术和髌骨脱位修复手术的麻醉。这些动物被归类为ASA I,在临床和实验室测试中没有出现变化。所有的狗都被麻醉并由麻醉师进行监测,并进行仔细的多参数评估。接近试验结束时,所有的狗都静脉注射美洛昔康,使用的药物具有相同的商业表现和浓度,但具有不同的批号和不同的月份。在不到一分钟的时间里,这些动物表现出明显的低血压,血压值接近30毫米汞柱或多普勒听不到。这些动物没有皮肤症状,只有低血压和其中一只的心率下降。所有犬均立即静脉注射麻黄碱和阿托品治疗心动过缓患者。经过紧急治疗,狗显示稳定的生命体征,没有并发症或需要额外的干预。事件发生后,这三只狗没有表现出任何临床、行为或实验室变化的迹象。
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Hypersensitivity reaction after intravenous administration of meloxicam in dogs - case report
ABSTRACT Although rarely reported in veterinary medicine, this article shows three cases of dogs that presented anaphylactic reactions after intravenous administration of meloxicam at therapeutic doses. Three dogs of different breeds and ages were submitted to anesthesia for surgical procedures of ovariohysterectomy and repair of patellar luxation. The animals were classified as ASA I and did not present changes in clinical and laboratory tests. All dogs were anesthetized and monitored by anesthesiologists, with careful multiparametric evaluation. Near the end of the procedures, meloxicam was administered intravenously in all dogs, and the drug used had the same commercial presentation and concentration, but with different lot numbers and with different months. For less than a minute, the animals showed significant hypotension, with pressure values close to 30 mmHg or inaudible by Doppler. The animals had no skin signs, only hypotension and a decrease in heart rate in one of them. All dogs were immediately treated with intravenous ephedrine and atropine in the bradycardic patient. After the emergency treatment, the dogs showed stabilized vital signs, with no complications or need for additional intervention. After the event, the three dogs showed no signs of clinical, behavioral or laboratory changes.
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来源期刊
CiteScore
0.80
自引率
25.00%
发文量
111
审稿时长
9-18 weeks
期刊介绍: Publica artigos originais de pesquisa sobre temas de medicina veterinária, zootecnia, tecnologia e inspeção de produtos de origem animal e áreas afins relacionadas com a produção animal. Atualmente a revista mantém 628 permutas (419 internacionais e 209 nacionais), sendo um verdadeiro suporte para o recebimento de periódicos pela Biblioteca da Escola. A partir de 1999, a Escola de Veterinária delegou à FEP MVZ Editora o encargo do gerenciamento e edição de todas suas publicações, inclusive do Arquivo, ficando somente com o apoio logístico (instalações, equipamentos, pessoal etc.). O apoio financeiro é exercido pelo CNPq/FINEP e pela própria FEP MVZ.
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