妊娠肥胖患者假性脑瘤1例

Nga Tran, James Liu, Paige Harrison, Jefferson Jones II
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摘要

脑假性肿瘤(PTC),特发性颅内高压,是一种严重的疾病,与妊娠最相关。据信这些症状是由于脑卒中容量增加和液体潴留最终导致颅内压升高所致。这种增加的压力可导致脑水肿和视神经纤维功能障碍。PTC的初步检查是进行计算机断层扫描(CT)或磁共振成像(MRI)脑部扫描,以排除可能引起头痛的结构异常。腰椎穿刺可迅速缓解症状并明确诊断PTC;然而,最终的治疗是乙酰唑胺通过抑制碳酸酐酶减轻颅内压。病例报告:本病例报告讨论了一个假性脑瘤如何影响一位29岁女性的妊娠,她表现为头痛、视力模糊、眼痛和腹痛。她的怀孕因几种合并症而复杂化。超声显示可行的宫内妊娠,而MRI无头部对比显示双侧乳头水肿。她接受乙酰唑胺治疗,并接受了原发性低横切面剖宫产由于胎儿畸形和假脑瘤的诊断。结论:PTC的症状被认为是一个更大的诊断,影像学证实颅内压升高是必要的。PTC的初步检查是进行CT或MRI脑部扫描,以排除可能引起头痛的结构异常。腰椎穿刺可以缓解症状并明确诊断PTC。最终的治疗是乙酰唑胺通过抑制碳酸酐酶减轻颅内压。
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Pseudotumor cerebri in pregnant obese patient: A case report
Introduction: Pseudotumor cerebri (PTC), idiopathic intracranial hypertension, is a serious condition that is most associated with pregnancy. It is believed that symptoms are due to increased stroke volume and fluid retention ultimately increasing intracranial pressure. This increased pressure can lead to cerebral edema and dysfunction of the optic nerve fibers. The initial workup for PTC is conducting a computed tomography (CT) or magnetic resonance imaging (MRI) brain scan to rule out structural abnormalities that may induce a headache. A lumbar puncture can be performed to acutely relieve the symptoms and definitively diagnose PTC; however, the definitive treatment is acetazolamide through the inhibition of carbonic anhydrase alleviating intracranial pressure. Case Report: This case report discusses how a pseudotumor cerebri affected the pregnancy of a 29-year-old female who presented with headache, blurry vision with eye pain, and abdominal pain. Her pregnancy was complicated by several comorbidities. Ultrasound showed a viable intrauterine pregnancy, while an MRI without contrast of the head revealed bilateral papilledema. She was treated with acetazolamide and underwent a primary low transverse cesarean section due to fetal malpresentation and pseudotumor cerebri diagnosis. Conclusion: It is imperative that symptoms of PTC are recognized as a larger diagnosis and that imaging confirms the increased intracranial pressure. The initial workup for PTC is conducting a CT or MRI brain scan to rule out structural abnormalities that may induce a headache. A lumbar puncture can relieve the symptoms and definitively diagnose PTC. The definitive treatment is acetazolamide through the inhibition of carbonic anhydrase alleviating intracranial pressure.
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