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Prenatal diagnosis, management, and outcomes of urinary tract anomalies 泌尿道异常的产前诊断、管理和结果
Pub Date : 2024-07-24 DOI: 10.5348/100169z08km2024rv
Klara S Missling, Sarah Araji, Kimberly S Sullivan
Congenital urinary tract anomalies are one of the more common defects noted on prenatal ultrasound. There are a variety of anomalies that can occur with a broad spectrum of outcomes with different degrees of severity based on pathologic processes. Ultrasound is the imaging modality utilized to allow visualization of the urinary tract system to diagnose these anomalies. We provide a review of these classifications with imaging and diagnostic recommendations, as well as epidemiology and associated defects. The aim of this review is to bring a clinically relevant and succinct understanding of congenital urinary tract anomalies and considerations for their various pathologies
先天性尿路畸形是产前超声检查中较常见的缺陷之一。先天性泌尿道畸形种类繁多,根据病理过程的不同,畸形的严重程度也各不相同。超声波是诊断这些畸形的一种成像方式,可用于观察泌尿道系统。我们对这些分类进行了综述,并提供了成像和诊断建议,以及流行病学和相关缺陷。本综述的目的是让临床医生简明扼要地了解先天性泌尿道异常及其各种病理的注意事项。
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引用次数: 0
Primary omental ectopic pregnancy after frozen-thawed single embryo transfer: A case report and review of the literature 冷冻解冻单胚胎移植后的原发性网膜异位妊娠:病例报告和文献综述
Pub Date : 2024-04-18 DOI: 10.5348/100170z08kk2024cr
Katherine Koniares, P. Godiwala, Claudio Benadiva, A. DiLuigi
Introduction: The objective of this case report is to present the first known case of a primary omental ectopic pregnancy following frozen-thawed embryo transfer. Case Report: A 35-year-old G0 female with severe male factor infertility underwent a frozen-thawed single embryo transfer. Serial transvaginal ultrasounds and beta human chorionic gonadotropin levels led to the diagnosis of ectopic pregnancy. The patient did not respond to medical management with methotrexate. On laparoscopy, an ectopic pregnancy was diagnosed on the greater omentum. The pregnancy was resected with the LigaSure device. Pathology evaluation was consistent with an omental ectopic pregnancy. Conclusion: Although rare, omental ectopic pregnancy should remain in the differential in the setting of a pregnancy of unknown location.
导言:本病例报告旨在介绍第一例已知的冷冻解冻胚胎移植后原发性网膜异位妊娠病例。病例报告:一名 35 岁的 G0 女性,患有严重的男性因素不孕症,接受了冻融单胚胎移植手术。连续的经阴道超声波检查和β人类绒毛膜促性腺激素水平导致了异位妊娠的诊断。患者对甲氨蝶呤药物治疗没有反应。腹腔镜检查发现,大网膜上有异位妊娠。使用 LigaSure 装置切除了妊娠。病理评估结果与网膜异位妊娠一致。结论大网膜异位妊娠虽然罕见,但在妊娠位置不明的情况下仍应作为鉴别诊断。
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引用次数: 0
Vulvar adenofibroma and pregnancy: A case study, at the regional hospital of Thiès 外阴腺纤维瘤与妊娠:Thiès 地区医院的病例研究
Pub Date : 2023-12-22 DOI: 10.5348/100165z08lg2023cr
Lamine Gueye, M. Thiam, O. Thiam, TL Bentefouet, O. Gassama, Pape Abdoulaye Ba, N. Dabo, ML Cissé
Introduction: Benign vulvar epithelial tumors developing from glandular structures are rare. Given the resemblance of vulvar fibroadenomas to those of mammary locations, some authors have put forward the hypothesis of development from accessory mammary glands. Case Report: We report a case of hyperalgesic giant vulvar fibroadenoma occurring in a 22-year-old female patient at 28 weeks, 3 days gestation. She was admitted for a painful mass on the right labia majora that had been present for two years, with a remarkable increase in volume during pregnancy. Faced with the acute vulvar pain and the discomfort caused by the mass, the decision to perform a vulvar lumpectomy was made and carried out semi-urgently, leading to the excision of a mass weighing 1103 grams. Microscopic examination revealed an adenofibroma. The patient gave birth vaginally at 38 weeks of gestation to a male baby weighing 3115 grams, 10 weeks after lumpectomy. Conclusion: Fibroadenoma is a benign tumor located in most cases in the breast, its location in the vulva is rare and can lead to a diagnostic delay. Surgical treatment by complete excision allows healing.
导言:从腺体结构发展而来的良性外阴上皮肿瘤非常罕见。鉴于外阴纤维腺瘤与乳腺部位的纤维腺瘤相似,一些学者提出了从乳腺附属腺体发展而来的假说。病例报告:我们报告了一例疼痛剧烈的巨大外阴纤维腺瘤病例,患者为 22 岁女性,妊娠 28 周零 3 天。她因右侧大阴唇肿块疼痛入院,该肿块已存在两年,在妊娠期间体积明显增大。面对剧烈的外阴疼痛和肿块带来的不适,医生决定进行外阴肿块切除术,并以半手术方式进行,最终切除了一个重达 1103 克的肿块。显微镜检查显示这是一个腺纤维瘤。肿块切除术后 10 周,患者在妊娠 38 周时经阴道产下一名男婴,重 3115 克。结论:纤维腺瘤是一种良性肿瘤:纤维腺瘤是一种良性肿瘤,大多数情况下位于乳房,而位于外阴的纤维腺瘤比较罕见,可能导致诊断延误。完全切除的手术治疗可使肿瘤痊愈。
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引用次数: 0
Left labial edema after kidney transplantation 肾移植后左侧唇水肿
Pub Date : 2023-12-12 DOI: 10.5348/100164z08am2023cr
Andrea Salcedo, Alexandra Maidan
Introduction: The differential diagnoses for labial edema are diverse. Labial edema after a kidney transplantation requires a thorough understanding of the various common and uncommon causes. Comprehensive history taking, physical examination, and awareness of anatomical knowledge will lead to proper diagnosis and treatment. Case Report: We present the case of an 18-year-old female with a past medical history of end stage renal disease secondary to bilateral atrophic kidneys and grade 3 vesicoureteral reflux status post deceased donor kidney transplant. She presented to the emergency department on postoperative day 5 due to uncontrolled hypertension and significant left labia minora edema with extreme pain to palpation. Gynecology evaluation and consultation determined the lesion was not suspicious for infection, abscess, or hematoma, and supportive care and conservative measures were initiated. Computed tomography (CT) was performed to rule out other causes of the anasarca, and after conservative management and doses of furosemide on hospital days 3 and 4, the patient showed improvement of the labial edema and blood pressure. Conclusion: A comprehensive differential diagnoses with reliance on anatomy and potential anomalies will lead clinicians and surgeons to properly treat potential postoperative complications. In this case, a thorough understanding of Mullerian anatomy and hemodynamic balance with implementation of conservative measures postoperatively resulted in resolution of the patient’s symptoms.
简介唇水肿的鉴别诊断多种多样。肾移植后出现唇水肿需要全面了解各种常见和不常见的原因。全面的病史采集、体格检查和解剖学知识将有助于正确诊断和治疗。病例报告:本病例为一名 18 岁女性,既往病史为双侧萎缩性肾脏继发终末期肾病,膀胱输尿管反流 3 级,死体肾移植术后。术后第 5 天,她因无法控制的高血压和左侧小阴唇明显水肿并伴有极度触痛而来到急诊科就诊。妇科评估和会诊确定病变没有感染、脓肿或血肿的可疑之处,并开始采取支持性护理和保守措施。在住院第 3 天和第 4 天,经过保守治疗和服用呋塞米后,患者的阴唇水肿和血压有所改善。结论依靠解剖学和潜在异常进行全面的鉴别诊断将引导临床医生和外科医生正确处理潜在的术后并发症。在本病例中,通过对 Mullerian 解剖学和血液动力学平衡的透彻了解以及术后采取的保守措施,患者的症状得到了缓解。
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引用次数: 0
Bilateral tubal pregnancy: An unusual presentation of a rare case 双侧输卵管妊娠:罕见病例的不寻常表现
Pub Date : 2023-11-10 DOI: 10.5348/100163z08yd2023cr
Wynn Thi Da, Hannah Wright
Introduction: Bilateral tubal pregnancy (BTP) is the rarest form of ectopic pregnancy. The reported incidence of spontaneous BTP is 5 in 1 million deliveries. Case Report: A 34-year-old woman with a previous diagnosis of right tubal pregnancy who had undergone surgery three weeks before presented with persistent pregnancy symptoms and abdominal pain prompting further investigation. Subsequently, bilateral tubal pregnancy was diagnosed after she underwent a second surgery for another ectopic pregnancy on the left side of the tube. Notably, both ectopic pregnancies were confirmed by histological examination. Conclusion: This case highlights the importance of clinical awareness of the possibility of bilateral tubal pregnancy even after a patient has recently undergone surgery for an ectopic pregnancy.
双侧输卵管妊娠(BTP)是最罕见的异位妊娠。据报道,自发性BTP的发生率为百万分之五。病例报告:一名34岁女性,先前诊断为右侧输卵管妊娠,三周前接受手术,出现持续妊娠症状和腹痛,促使进一步调查。随后,由于左侧输卵管的另一个异位妊娠,她接受了第二次手术,诊断为双侧输卵管妊娠。值得注意的是,两例异位妊娠均经组织学检查证实。结论:本病例强调了临床认识双侧输卵管妊娠可能性的重要性,即使患者最近接受了异位妊娠手术。
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引用次数: 0
Recurrent ipsilateral interstitial ectopic pregnancy after salpingectomy 输卵管切除术后复发性同侧间质性异位妊娠
Pub Date : 2023-11-06 DOI: 10.5348/100161z08fz2023cr
Federica Zammit, Sarah Sultana Grixti, Charles Savona-Ventura
Introduction: This case highlights the long-term obstetric risks following salpingectomy. These include recurrent ipsilateral interstitial ectopic pregnancy and uterine rupture. Case Report: A 29-year-old lady presented with acute abdominal pain as well as signs and symptoms of hemorrhagic shock at 14 weeks of gestation. She was subsequently diagnosed with a ruptured right-sided interstitial ectopic pregnancy, which was managed surgically. The patient had a past history of open salpingo-oophorectomy for a complicated right-sided ectopic pregnancy involving the ovary at 12 weeks of gestation in her previous pregnancy. A subsequent pregnancy a year later was complicated by impending uterine rupture at 30 weeks of gestation. A healthy baby was delivered by Cesarean section. Conclusion: A meticulous surgical technique is of the essence when performing a salpingectomy for whatever pathology. The risk of a recurrent ipsilateral interstitial ectopic pregnancy must always be considered. Also, the risk of antenatal and intrapartum uterine rupture must be addressed in future pregnancies following interstitial pregnancies.
本病例强调了输卵管切除术后的长期产科风险。这些包括复发性同侧间质性异位妊娠和子宫破裂。病例报告:一位29岁的女性在妊娠14周时表现为急性腹痛以及失血性休克的体征和症状。她随后被诊断为右侧间质性宫外孕破裂,手术治疗。患者曾在妊娠12周时因复杂的右侧异位妊娠累及卵巢而行开放输卵管卵巢切除术。一年后她又怀孕了,在怀孕30周时子宫破裂。剖腹产生下了一个健康的婴儿。结论:无论何种病理,在进行输卵管切除术时,一丝不苟的手术技术是至关重要的。复发同侧间质性异位妊娠的风险必须始终考虑。此外,产前和产时子宫破裂的风险必须解决在今后怀孕后的间质妊娠。
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引用次数: 0
Pancreatic ductal adenocarcinoma (intestinal-type differentiation) presenting as ovarian metastases: A case report 胰腺导管腺癌(肠型分化)表现为卵巢转移:1例报告
Pub Date : 2023-10-31 DOI: 10.5348/100159z08ef2023cr
Emily Fronk, Annalyn Welp, Megan Dibbern, Anne Mills, Leigh Cantrell
Introduction: Metastasis of pancreatic adenocarcinoma to the ovaries is uncommon and can clinically present similarly to primary ovarian disease, presenting challenges for diagnosis. Immunohistochemical staining is typically useful in distinguishing ovarian primaries from ovarian metastasis. A newer and rarer variant of pancreatic adenocarcinoma, that with intestinal-type differentiation, has not previously been reported as metastasizing to the ovary. Its diagnosis is particularly difficult due to the overlap in staining patterns with primary ovarian neoplasms. Case Report: This case report presents the case of a 60-year-old female who presented with non-specific abdominal symptoms and was found to have a large adnexal mass. Imaging showed additional lesions in the peritoneum, pancreas, and liver. She underwent biopsy with morphology and immunohistochemical staining consistent with pancreatic ductal adenocarcinoma with intestinal-type differentiation. She was started on FOLFIRINOX therapy but ultimately opted to pursue comfort care due to disease progression. Conclusion: Although rare, with this being the first report of this disease course to our knowledge, clinicians should be aware of this possibility, as it impacts choice of treatment.
摘要:胰腺腺癌转移到卵巢并不常见,其临床表现与原发性卵巢疾病相似,给诊断带来了挑战。免疫组织化学染色通常用于区分卵巢原发和卵巢转移。一种较新的和罕见的胰腺腺癌变异,具有肠型分化,以前没有报道转移到卵巢。由于与原发卵巢肿瘤的染色模式重叠,其诊断特别困难。病例报告:本病例报告提出的情况下,60岁的女性谁提出了非特异性腹部症状,并发现有一个大的附件肿块。影像学显示腹膜、胰腺和肝脏有其他病变。她接受了活检,形态学和免疫组织化学染色与肠型分化的胰腺导管腺癌一致。她开始接受FOLFIRINOX治疗,但由于疾病进展,最终选择了舒适护理。结论:虽然罕见,但据我们所知,这是第一次报道这种疾病过程,临床医生应该意识到这种可能性,因为它会影响治疗的选择。
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引用次数: 0
Spontaneous bilateral tubal ectopic pregnancy: A case report 自发性双侧输卵管异位妊娠1例
Pub Date : 2023-09-28 DOI: 10.5348/100158z08km2023cr
Keturah Murray, Damian Best
Unilateral tubal ectopic pregnancies (UTEP) are commonly encountered by physicians. Bilateral tubal ectopic pregnancies (BTEPs), however, are rare and due to the identical clinical presentations of BTEP and UTEP, there is a significant degree of diagnostic difficulty for the former, requiring a high index of suspicion. It should be considered a possibility in any newly pregnant woman of child-bearing age. The purpose of this article is to provide the reader with an example of a clinical presentation of BTEP, and a discourse on management of these patients. We present a case of a 27-year-old patient, who was seen at the emergency department of the Queen Elizabeth Hospital, Barbados, with signs and symptoms of a ruptured ectopic pregnancy. Intraoperative findings included a ruptured left ectopic pregnancy and an intact right fallopian tubal ectopic pregnancy. Left salpingectomy and right salpingostomy were performed, conserving the intact tube; her recovery was solely complicated by a superficial surgical site infection.
单侧输卵管异位妊娠(UTEP)是医生经常遇到的。然而,双侧输卵管异位妊娠(BTEP)是罕见的,由于BTEP和UTEP的临床表现相同,前者的诊断难度很大,需要高度怀疑。任何新怀孕的育龄妇女都应考虑这种可能性。本文的目的是为读者提供一个BTEP临床表现的例子,以及对这些患者管理的论述。我们提出了一个27岁的病人的情况下,谁是看到在急诊部伊丽莎白女王医院,巴巴多斯,与迹象和症状的破裂异位妊娠。术中发现包括左侧异位妊娠破裂和右侧输卵管完整异位妊娠。行左侧输卵管切除术和右侧输卵管造口术,保留完整输卵管;她的恢复仅仅是由于手术部位的浅表感染而复杂化。
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引用次数: 0
Pseudotumor cerebri in pregnant obese patient: A case report 妊娠肥胖患者假性脑瘤1例
Pub Date : 2023-01-01 DOI: 10.5348/100160z08nt2023cr
Nga Tran, James Liu, Paige Harrison, Jefferson Jones II
Introduction: Pseudotumor cerebri (PTC), idiopathic intracranial hypertension, is a serious condition that is most associated with pregnancy. It is believed that symptoms are due to increased stroke volume and fluid retention ultimately increasing intracranial pressure. This increased pressure can lead to cerebral edema and dysfunction of the optic nerve fibers. The initial workup for PTC is conducting a computed tomography (CT) or magnetic resonance imaging (MRI) brain scan to rule out structural abnormalities that may induce a headache. A lumbar puncture can be performed to acutely relieve the symptoms and definitively diagnose PTC; however, the definitive treatment is acetazolamide through the inhibition of carbonic anhydrase alleviating intracranial pressure. Case Report: This case report discusses how a pseudotumor cerebri affected the pregnancy of a 29-year-old female who presented with headache, blurry vision with eye pain, and abdominal pain. Her pregnancy was complicated by several comorbidities. Ultrasound showed a viable intrauterine pregnancy, while an MRI without contrast of the head revealed bilateral papilledema. She was treated with acetazolamide and underwent a primary low transverse cesarean section due to fetal malpresentation and pseudotumor cerebri diagnosis. Conclusion: It is imperative that symptoms of PTC are recognized as a larger diagnosis and that imaging confirms the increased intracranial pressure. The initial workup for PTC is conducting a CT or MRI brain scan to rule out structural abnormalities that may induce a headache. A lumbar puncture can relieve the symptoms and definitively diagnose PTC. The definitive treatment is acetazolamide through the inhibition of carbonic anhydrase alleviating intracranial pressure.
脑假性肿瘤(PTC),特发性颅内高压,是一种严重的疾病,与妊娠最相关。据信这些症状是由于脑卒中容量增加和液体潴留最终导致颅内压升高所致。这种增加的压力可导致脑水肿和视神经纤维功能障碍。PTC的初步检查是进行计算机断层扫描(CT)或磁共振成像(MRI)脑部扫描,以排除可能引起头痛的结构异常。腰椎穿刺可迅速缓解症状并明确诊断PTC;然而,最终的治疗是乙酰唑胺通过抑制碳酸酐酶减轻颅内压。病例报告:本病例报告讨论了一个假性脑瘤如何影响一位29岁女性的妊娠,她表现为头痛、视力模糊、眼痛和腹痛。她的怀孕因几种合并症而复杂化。超声显示可行的宫内妊娠,而MRI无头部对比显示双侧乳头水肿。她接受乙酰唑胺治疗,并接受了原发性低横切面剖宫产由于胎儿畸形和假脑瘤的诊断。结论:PTC的症状被认为是一个更大的诊断,影像学证实颅内压升高是必要的。PTC的初步检查是进行CT或MRI脑部扫描,以排除可能引起头痛的结构异常。腰椎穿刺可以缓解症状并明确诊断PTC。最终的治疗是乙酰唑胺通过抑制碳酸酐酶减轻颅内压。
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引用次数: 0
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Journal of Case Reports and Images in Obstetrics and Gynecology
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