外置清络散治疗外周静脉导管性静脉炎的随机对照研究

IF 0.4 4区 医学 Q4 PHARMACOLOGY & PHARMACY Indian Journal of Pharmaceutical Sciences Pub Date : 2023-01-01 DOI:10.36468/pharmaceutical-sciences.spl.708
Jiayue Li, Yuan Zhang, Ying Zhang, Peng Guo, Ning Guo, Xiaoyan Zheng, Yuan Tian
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引用次数: 0

摘要

本研究的目的是评价中药软膏清络散对外周静脉置管患者静脉炎的预防作用。我们进行了一项单中心随机对照试验,将127名符合条件的患者随机分为两组;实验组和对照组。在基线、24小时、48小时和72小时测量疼痛强度和静脉炎程度,并获取所有患者的人口统计学信息(年龄、性别、体重指数)、静脉炎部位、导管停留时间、血红蛋白和白细胞。与对照组相比,实验组在干预后24 h、48 h、72 h静脉炎发生率和疼痛强度均明显降低。两组患者的人口统计学信息(年龄、性别、体重指数)、静脉炎部位、置管时间、血红蛋白、白细胞等差异均无统计学意义。外置静脉导管患者外置清络散治疗是降低静脉炎发生率的有效方法。
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A Randomized Controlled Study to Observe the Efficacy of External Treatment with Qingluo San on Phlebitis from Peripheral Venous Catheter
The purpose of this study is to evaluate the efficacy of the Chinese herbal ointment Qingluo San in preventing phlebitis in patients with peripheral venous catheters. We conducted a single-center randomized controlled trial, in which 127 eligible patients were assigned randomly to one of two groups; the experimental group or the control group. The degrees of pain intensity and phlebitis were measured at baseline, 24 h, 48 h and 72 h. Demographic information (age, gender, body mass index) and phlebitis sites, catheter dwell time, hemoglobin and white blood cells were obtained from all patients. Compared with the control group, the experimental group showed significantly lower incidence of phlebitis and pain intensity at 24 h, 48 h and 72 h after intervention. However, there were no significant differences about the demographic information (age, gender, body mass index) and phlebitis sites, catheter dwell time, hemoglobin and white blood cells between these two groups. In patients with peripheral venous catheters, external treatment with Qingluo San was an effective method for decreasing the incidence of phlebitis.
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期刊介绍: The Indian Journal of Pharmaceutical Sciences (IJPS) is a bi-monthly Journal, which publishes original research work that contributes significantly to further the scientific knowledge in Pharmaceutical Sciences (Pharmaceutical Technology, Pharmaceutics, Biopharmaceutics, Pharmacokinetics, Pharmaceutical/Medicinal Chemistry, Computational Chemistry and Molecular Drug Design, Pharmacognosy and Phytochemistry, Pharmacology and Therapeutics, Pharmaceutical Analysis, Pharmacy Practice, Clinical and Hospital Pharmacy, Pharmacovigilance, Pharmacoepidemiology, Pharmacoeconomics, Drug Information, Patient Counselling, Adverse Drug Reactions Monitoring, Medication Errors, Medication Optimization, Medication Therapy Management, Cell Biology, Genomics and Proteomics, Pharmacogenomics, Bioinformatics and Biotechnology of Pharmaceutical Interest). The Journal publishes original research work either as a Full Research Paper or as a Short Communication. Review Articles on current topics in Pharmaceutical Sciences are also considered for publication by the Journal.
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