构建AgNPs包被纳米微胶囊,有效增强抗菌活性

IF 2.9 4区 医学 Q1 Medicine Journal of biomedical nanotechnology Pub Date : 2023-09-01 DOI:10.1166/jbn.2023.3600
Ke He, Yanqi Wu, Yanting He, Jun Jin, Qing Hu, Jia Wu, Guangxun Cui, Jun Zhang, Yong Liu
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引用次数: 0

摘要

随着人们对生活环境要求的不断提高,健康、绿色的生活材料受到了市场的青睐。纳米技术的发展为健康人居环境材料的研究和开发提供了新的方向。以纳米微胶囊为载体,制备含有高效抗菌剂的新型建筑涂料,可实现缓释和高效抗菌。对改善室内墙体细菌污染,提供清洁的生活环境具有重要的应用价值。采用一步法制备了包被纳米微胶囊(AgNPs@PS-NMP)的银纳米颗粒,用于杀灭金黄色葡萄球菌(S. aureus)。SEM结果表明,该材料的粒径在500 ~ 600 nm左右,粒径均匀,团聚程度小,形貌完整。Zeta电位约为−18.8 mV。分别考察了AgNPs@PS-NMP涂料的施工性能、亲水性和干燥时间。进一步研究了AgNPs@PS-NMP的抑菌活性。结果表明,该纳米微胶囊对金黄色葡萄球菌具有良好的杀灭效果,最低杀菌浓度(MBC)为28 μ g/mL。这些结果表明,AgNPs@PS-NMP作为一种新型涂料,不仅具有良好的涂层性能,而且具有优异的抗菌性能。它可以作为一种潜在的抗菌建筑材料用于医院、学校等场所。
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Constructed Nano-Microcapsule Coating Coated with AgNPs for Enhanced Antibacterial Activity Effectively
With the continuous improvement of people’s requirements for the living environment, healthy and green living materials have been favored by the market. The development of nanotechnology provides a new direction for the research and development of healthy human settlement materials. Nano-microcapsules are used as carriers to prepare new building coating materials with efficient antibacterial agents, which can achieve slow release and efficient antibacterial properties. It has important application value for improving bacterial pollution on indoor walls and providing a clean-living environment. Silver nanoparticles coated with nano-microcapsules (AgNPs@PS-NMP) were prepared by one-step method for killing Staphylococcus aureus ( S. aureus ). SEM results showed that the particle size was about 500–600 nm, the particle size was uniform, the degree of agglomeration was small, and the morphology was complete. The Zeta potential was approximately −18.8 mV. The coating construction performance, hydrophilicity, drying time of AgNPs@PS-NMP were investigated respectively. The antibacterial activity of AgNPs@PS-NMP was further studied. The results showed that the nano-microcapsules had a good killing effect on S. aureus , and the minimum bactericidal concentration (MBC) was 28 μ g/mL. These results suggest that AgNPs@PS-NMP, as a new type of coating, not only has good coating properties but also excellent antibacterial properties. It can be used as a potential antibacterial building material for hospitals, schools and other places.
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来源期刊
CiteScore
4.30
自引率
17.20%
发文量
145
审稿时长
2.3 months
期刊介绍: Information not localized
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