生物和非生物领域的多糖类杂化材料

Muhammad Bilal
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The appealing combination of biodegradability, non-toxicity, and biocompatibility displayed by these biopolymers, along with their diverse structural characteristics and desirable physical, biological, and chemical properties, has captured the interest of researchers from various disciplines. Consequently, there has been a substantial spike in the exploration of polysaccharides and their prospective applications in biotechnological fields, such as tissue engineering, gene delivery, drug delivery, wound dressing, cancer therapy, biosensing, and water treatment. Naturally occurring polysaccharides like starch, alginates, chitin, chitosan, cellulose, dextran, and hyaluronic acid, as well as their hybrid derivatives with multifunctional attributes, have garnered substantial interest in biotechnological, industrial, and biomedical applications. Additionally, nanostructured materials based on polysaccharides have demonstrated great promise in recent years, particularly in chemical and biomedical research, due to their abundance, excellent biocompatibility, biodegradability, cost-effectiveness, and non-toxic nature. Therefore, there has been a notable shift in focus towards hybrid materials, encompassing both micro- and nano-scale dimensions and their potential applications across various sectors in the modern world. Exploiting meticulously designed materials facilitates the creation of well-defined prototypes that enable a series of purposeful actions. This special edition spotlights the recent research in the design, development, and emerging applications of polysaccharides-based hybrid materials for biotechnological and biomedical purposes. 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引用次数: 0

摘要

政府、工业和最终用户对具有生物可降解性、碳中和性、环境友好性和对人类健康风险低的产品的需求日益增长。多糖是由糖苷键连接的单糖亚基组成的重要生物聚合物。不同的多糖表现出广泛的官能团,包括羟基、羧基、氨基、乙酰和磺酸,与其他生物分子相比,这有助于它们作为生物聚合物的多功能性。此外,多糖的生物加工具有简单、环保、经济、适合大规模生产的特点。这些生物聚合物具有生物可降解性、无毒性和生物相容性,以及它们不同的结构特征和理想的物理、生物和化学特性,引起了各个学科研究人员的兴趣。因此,对多糖及其在生物技术领域(如组织工程、基因传递、药物传递、伤口敷料、癌症治疗、生物传感和水处理)的潜在应用的探索出现了实质性的激增。天然存在的多糖,如淀粉、海藻酸盐、几丁质、壳聚糖、纤维素、葡聚糖和透明质酸,以及它们具有多功能属性的杂交衍生物,已经在生物技术、工业和生物医学应用中获得了极大的兴趣。此外,基于多糖的纳米结构材料近年来表现出巨大的前景,特别是在化学和生物医学研究中,由于其丰富,良好的生物相容性,可生物降解性,成本效益和无毒性质。因此,人们对混合材料的关注有了显著的转变,包括微观和纳米尺度及其在现代世界各个领域的潜在应用。利用精心设计的材料有助于创建定义良好的原型,从而实现一系列有目的的动作。本特别版重点介绍了生物技术和生物医学用途的多糖基混合材料的设计,开发和新兴应用方面的最新研究。所有发表在这期杂志上的文章都强调了纤维素、海藻酸盐、壳聚糖、淀粉和卡拉胶等材料在酶生产、胶囊化、靶向给药、药物控制释放、组织工程、药妆配方、食品包装和水/废水处理等方面的重要应用。我谨代表编委会向为本期特刊做出重要贡献的各位作者表示衷心的感谢。淀粉杂志致力于推进我们对生物技术中以多糖为基础的杂交材料的理解。Muhammad Bilal博士是波兰格但斯克格但斯克工业大学土木与环境工程学院卫生工程系副教授。他在上海交通大学获得博士学位,专攻生物工程和应用生物技术。他在科学和工程的各个领域以研究、评论、书籍章节和编辑型科学文章的形式发表了700多篇科学贡献。他的h指数为72,被引用超过22000次。他是《生物工程》(Taylor & Francis)、《微生物学前沿》、《化学工程前沿》和《环境科学前沿》(Frontiers)的副主编。他编辑了一些特刊和书籍,并在许多同行评议的期刊上担任科学审稿人。他的主要研究方向为生物工程、生物技术、生物催化、酶工程、固定化、废水处理、酶降解、危险污染物和新兴污染物的生物修复、废物管理和农业工业废物的价值化。
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Polysaccharides‐Based Hybrid Materials for Bio‐ and Non‐Bio Sectors
There is a growing demand from the government, industry, and end-users for products that possess biodegradability, carbon neutrality, environmental friendliness, and low risks to human health. Polysaccharides are vital biopolymers that consist of monosaccharide subunits connected by glycosidic linkages. Different polysaccharides exhibit a wide array of functional groups, including hydroxyl, carboxyl, amino, acetyl, and sulfonic acids, contributing to their versatility as biopolymers compared to other biomolecules. Furthermore, the bioprocessing of polysaccharides is characterized by its simplicity, environmental friendliness, cost-effectiveness, and suitability for large-scale production. The appealing combination of biodegradability, non-toxicity, and biocompatibility displayed by these biopolymers, along with their diverse structural characteristics and desirable physical, biological, and chemical properties, has captured the interest of researchers from various disciplines. Consequently, there has been a substantial spike in the exploration of polysaccharides and their prospective applications in biotechnological fields, such as tissue engineering, gene delivery, drug delivery, wound dressing, cancer therapy, biosensing, and water treatment. Naturally occurring polysaccharides like starch, alginates, chitin, chitosan, cellulose, dextran, and hyaluronic acid, as well as their hybrid derivatives with multifunctional attributes, have garnered substantial interest in biotechnological, industrial, and biomedical applications. Additionally, nanostructured materials based on polysaccharides have demonstrated great promise in recent years, particularly in chemical and biomedical research, due to their abundance, excellent biocompatibility, biodegradability, cost-effectiveness, and non-toxic nature. Therefore, there has been a notable shift in focus towards hybrid materials, encompassing both micro- and nano-scale dimensions and their potential applications across various sectors in the modern world. Exploiting meticulously designed materials facilitates the creation of well-defined prototypes that enable a series of purposeful actions. This special edition spotlights the recent research in the design, development, and emerging applications of polysaccharides-based hybrid materials for biotechnological and biomedical purposes. All the articles published in this issue underscore the significance of materials derived from cellulose, alginate, chitosan, starch, and carrageenan for various applications, including enzyme production, encapsulation, targeted drug delivery, controlled drug release, tissue engineering, cosmeceutical formulations, food packaging, and water/wastewater treatment. On behalf of the editorial board, I would like to extend sincere gratitude to all the authors who have made significant contributions to this special issue. The Starch journal is committed to advancing our understanding of polysaccharides-based hybrid materials in biotechnology. Dr. Muhammad Bilal is an associate professor at the Department of Sanitary Engineering, Faculty of Civil and Environmental Engineering, Gdansk University of Technology, Gdansk, Poland. He earned his Ph.D. from Shanghai Jiao Tong University, specializing in bioengineering and applied biotechnology. He has published more than 700 scientific contributions in the form of research, reviews, book chapters, and editorial-type scientific articles in various areas of Science and Engineering. He has an h-index of 72, along with more than 22 000 citations. He is associate editor of the Bioengineered (Taylor & Francis), Frontiers in Microbiology, Frontiers in Chemical Engineering, and Frontiers in Environmental Science (Frontiers). He has edited several special issues and books and serves as a scientific reviewer in numerous peer-reviewed journals. His main research activities are oriented to Bioengineering, Biotechnology, Bio-catalysis, Enzyme engineering, immobilization, Wastewater treatment, Enzymatic degradation, Bioremediation of hazardous and emerging pollutants, Waste management, and Valorization of agro-industrial wastes.
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