The relationship of central macular thickness with clinical grades of diabetic retinopathy

To assess central macular thickness (CMT) in diabetics with or without diabetic retinopathy (DR) and compare it with various clinical grades of DR. All patients attending the ophthalmic OPD fulfilling the inclusion and met no exclusion criteria were enrolled in this study. All eyes underwent comprehensive and standardized ophthalmic examination. The CMT was measured using spectral domain optical coherence tomography using Cirrus HD OCT Model 500. The mean CMT in cases is significantly greater than controls. It is also significantly greater in diabetics with DR as compared to diabetics without DR and it significantly varies with various grades of DR. The mean CMT is also increased in patients with diabetic macular edema (DME) and panretinal photocoagulation (PRP) untreated DR as compared to diabetics without DME and PRP treated DR respectively. Central macular thickness can be used as an indicator to monitor individuals with diabetes as it increased in diabetics and the presence of macular edema decreased in PRP treated eyes. It also varies with various grades of DR.