氧空位促进骨支架对抗细菌感染的芬顿反应

IF 16.1 1区工程技术 Q1 ENGINEERING, MANUFACTURING International Journal of Extreme Manufacturing Pub Date : 2023-10-20 DOI:10.1088/2631-7990/ad01fd

cijun shuai, Xiaoxin Shi, Feng Yang, Haifeng Tian, Pei Feng

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引用次数: 1

摘要

提出了用高能球磨法制备氧空位缺陷的方法。采用选择性激光烧结技术制备了具有个性化形状和多孔结构的支架。用抗菌材料将h2o2吸附在细菌感染部位。积累的h2o2可以提高Fenton反应效率，诱导更多的·OH。支架具有匹配的力学性能和良好的生物相容性。

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Oxygen vacancy boosting Fenton reaction in bone scaffold towards fighting bacterial infection

Highlights High-energy ball milling was proposed to construct oxygen vacancy defects. Scaffold with individualized shape and porous structure was fabricated by selective laser sintering. Antibacterial material was used to adsorb H 2 O 2 to the site of bacterial infection. The accumulated H 2 O 2 could amplify the Fenton reaction efficiency to induce more ·OH. The scaffold possessed matched mechanical properties and good biocompatibility.

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来源期刊

International Journal of Extreme Manufacturing Engineering-Industrial and Manufacturing Engineering

CiteScore

17.70

自引率

6.10%

发文量

审稿时长

12 weeks

期刊介绍： The International Journal of Extreme Manufacturing (IJEM) focuses on publishing original articles and reviews related to the science and technology of manufacturing functional devices and systems with extreme dimensions and/or extreme functionalities. The journal covers a wide range of topics, from fundamental science to cutting-edge technologies that push the boundaries of currently known theories, methods, scales, environments, and performance. Extreme manufacturing encompasses various aspects such as manufacturing with extremely high energy density, ultrahigh precision, extremely small spatial and temporal scales, extremely intensive fields, and giant systems with extreme complexity and several factors. It encompasses multiple disciplines, including machinery, materials, optics, physics, chemistry, mechanics, and mathematics. The journal is interested in theories, processes, metrology, characterization, equipment, conditions, and system integration in extreme manufacturing. Additionally, it covers materials, structures, and devices with extreme functionalities.