沧塘石斑鱼(Epinephelus sp.)感染VNN(病毒性神经坏死)后体内CD4反应中臂尾轮虫蛋白的研究

Nur Fauziyah Martiningsih, Uun Yanuhar, Mohammad Musa, Dwi Retna Kumalaningrum
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引用次数: 0

摘要

本研究探讨了Brachionus sp.蛋白对感染VNN的沧塘石斑鱼CD4免疫系统的影响。本研究的目的是测定具有抗病毒潜力的臂尾轮虫的蛋白质含量,并发现臂尾轮虫对CD4表达的益处,作为提高鱼体对VNN防御系统的指标。Brachionus sp.本身含有3条分子量分别为122.73 kDa、75.49 kDa和13.77 kDa的蛋白带,有望增强斑马鱼对VNN的免疫系统。以35µl、105µl和170µl/150 g沧石斑鱼剂量注射臂尾虫蛋白,以105µl/150 g沧石斑鱼剂量降低幅度最小。
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Exploration of Brachionus sp. Protein on the In Vivo Response of CD4 at Cantang Grouper (Epinephelus sp.) with VNN Infection (Viral Nervous Necrosis)
This study examines the function of Brachionus sp. protein on the Cluster Differentiation-4 (CD4) immune system in cantang grouper infected with VNN. The purpose of this study was to determine the protein content of Brachionus sp. which has the potential as an antivirus and to find out the benefits of Brachionus sp. on the expression of CD4 as an indicator of increased fish body defense system against VNN. Brachionus sp. itself contains three protein bands with molecular weights of 122.73 kDa, 75.49 kDa, and 13.77 kDa, which are expected to increase the immune system against VNN on cantang grouper. Protein injection of Brachionus with doses of 35 µl, 105 µl and 170 µl /150 g cantang grouper, showed that the lowest decrease was at a dose of 105 µl/150 gram cantang groupers.
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