约旦首例耳念珠菌病例报告

IF 2.1 Q3 MICROBIOLOGY Microbiology Research Pub Date : 2023-10-03 DOI:10.3390/microbiolres14040107
Jamal Wadi Al-Ramahi, Rola Ali Ghanem, Omar Helmy Sayyouh, Dima Al-Jammal, Mayar M. Said, Salwa Nasrat, Mona El-Shokry, Mahmoud Gazo, Tamer Saied Osman
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引用次数: 0

摘要

耳念珠菌(C. auris)是一种机会性芽殖酵母,已在41个国家发现,包括中东的几个国家。这种病原体对抗真菌药物的获得性耐药性及其形成生物膜的能力使其能够在医院表面和医疗设备上存活长达14天,从而影响了医院的感染预防措施,这引起了全球越来越多的关注。在本报告中,我们报告了从居住在约旦的一名48岁女性的尿液样本中分离到的首例(报告的)耳念珠菌病例。病人入院五天后病死。该分离物通过约旦国家监测系统进行回顾性鉴定,并通过实时PCR得到证实。采用微肉汤稀释法进行抗真菌药敏试验,发现该菌株对所有抗真菌药物均敏感。总的来说,该报告强调需要积极监测,以便快速识别金黄色葡萄球菌定殖的高危患者。它还强调了了解C. auris易感性模式的进化间差异对促进预防和治疗策略的发展的重要性。
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Report of the First Case of Candida auris Identified in Jordan
Candida auris (C. auris) is an opportunistic budding yeast that has been identified across 41 countries, including several countries in the Middle East. The increasing global concern stems from the pathogen’s acquired resistance to antifungal drugs and its ability to form biofilms, which allows it to survive on hospital surfaces and medical devices for up to 14 days, compromising infection prevention measures in hospitals. In this report, we present the first (reported) case of C. auris isolated from a urine sample from a 48-year-old female living in Jordan. The patient succumbed to illness five days following admission to hospital. The isolate was identified retrospectively through the national surveillance system in Jordan and was confirmed by real-time PCR. Antifungal susceptibility was carried out using the microbroth dilution technique and the isolate was found to be susceptible to all tested antifungal drugs. Overall, the report emphasizes the need for active surveillance for the rapid identification of high-risk patients colonized with C. auris. It also stresses the importance of understanding the inter-clade difference in the susceptibility pattern of C. auris to facilitate the development of preventive and therapeutic strategies.
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来源期刊
Microbiology Research
Microbiology Research MICROBIOLOGY-
CiteScore
1.90
自引率
6.70%
发文量
62
审稿时长
10 weeks
期刊介绍: Microbiology Research is an international, online-only, open access peer-reviewed journal which publishes original research, review articles, editorials, perspectives, case reports and brief reports to benefit researchers, microbiologists, physicians, veterinarians. Microbiology Research publishes ‘Clinic’ and ‘Research’ papers divided into two different skill and proficiency levels: ‘Junior’ and ‘Professional’. The aim of this four quadrant grid is to encourage younger researchers, physicians and veterinarians to submit their results even if their studies encompass just a limited set of observations or rely on basic statistical approach, yet upholding the customary sound approach of every scientific article.
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