禽沙门氏菌病乳灭活疫苗制备及质量控制的最佳工艺条件研究

I.A. Darouskikh
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摘要

本文介绍了用于预防鸟类沙门氏菌病的灭活乳化疫苗的生产和质量控制的最佳参数的开发,沙门氏菌免疫原性有效疫苗株的分离和选择的数据。本文提供了在白俄罗斯共和国家禽养殖场条件下分离用于形成疫苗菌株的病原体的数据。这项工作的重要性和相关性在于,疫苗菌株的选择,考虑到每个单独的流行区沙门氏菌菌株,是必要的,以创造最有效的免疫原性疫苗。
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DEVELOPMENT OF OPTIMUM PARAMETERS FOR OBTAINING AND QUALITY CONTROL INACTIVATED EMULSIFIED VACCINE FOR THE PREVENTION OF AVIAN SALMONELLOSIS
The article presents data on the development of optimal parameters for the production and quality control of an inactivated emulsified vaccine for the prevention of salmonellosis in birds, the isolation and selection of immunogenically effective vaccine strains of Salmonella. The data on the isolation of pathogens for the formation of vaccine strains in the conditions of poultry farms of the Republic of Belarus are given. The importance and relevance of this work lies in the fact that the selection of vaccine strains, taking into account the circulating Salmonella strains in each individual endemic zone, is necessary to create the most immunogenically effective vaccines.
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