荆芥叶提取物的定性植物化学筛选及抗氧化和抗炎活性评价

Najmun Naher Sonia, Minhajur Rahman, Animesh Biswas
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引用次数: 0

摘要

本研究的目的是筛选荆芥叶提取物的植物化学成分,并评价其抗氧化和抗炎作用。在植物化学研究中发现了生物碱、糖苷、单宁、萜类、皂苷、酞菁、类固醇、奎宁、酚、香豆素和类黄酮。山楂叶提取物对DPPH自由基清除的IC50值为154.33µg/ml(标准值:IC50 = 25.48µg/ml);对白蛋白变性抑制的IC50值为218.8µg/ml(标准值:IC50 = 33.74µg/ml)。结果表明,桄子花叶片含有多种具有清除DPPH和抑制白蛋白变性的重要次生代谢产物,具有抗氧化和抗炎作用。j . Bio-Sci。30(2): 01-11, 2022
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Qualitative Phytochemical Screening, Evaluation of Antioxidant and Anti-Inflammatory Potentials of Vitex pinnata L. Leaf Extract
The purpose of the study was to screen phytochemicals and assess the antioxidant as well as anti-inflammatory properties of Vitex pinnata leaf extracts. Alkaloids, glycosides, tannins, terpenoids, saponins, phlobatannins, steroids, quinine, phenol, coumarins, and flavonoids were found during the phytochemical investigation. V. pinnata leaf extract exhibited an IC50 value of 154.33 µg/ml in the DPPH free radical scavenging assay (standard: IC50 = 25.48 µg/ml) IC50 value of 218.8 µg/ml in the albumin denaturation inhibition assay (standard: IC50 = 33.74 µg/ml). According to the findings, the leaves of V. pinnata contain a variety of pharmaceutically important secondary metabolites capable of scavenging DPPH and inhibiting albumin denaturation, demonstrating their antioxidant and anti-inflammatory properties. J. Bio-Sci. 30(2): 01-11, 2022
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