尼日利亚三角洲州阿萨巴联邦医疗中心艾滋病毒患者中结核分枝杆菌的流行情况

Odiase, Edgar Onyeka, Olley Mitsan, Daniel Ohilebo Ugbomoiko, Theophilus Ogie Erameh, Ezekiel Dauda Gambo, Ofili Sandra Kanwulia, Muhammad Adamu Ibrahim, Paul Yiran Ntasin
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 Methodology: A total of 188 samples were obtained from known HIV patients. The patients were selected by random sampling technique. The samples were analysed using GeneXpert machine (GX2.1 model) with the nuclei acid amplification (NAA) of DNA mycobacterium tuberculosis complex (MTBC) and resistance to rifampicin. Demographic data of participants were obtained through questionnaires.
 Results: Out of 188 samples from HIV patients analyzed, MTB was detected in 13 (8.7%) patients with the highest prevalence recorded among male subjects 6(12%). Age group 19-29 was the most prevalent of MTB among the test subjects.
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引用次数: 0

摘要

目的:本研究旨在确定尼日利亚三角洲州阿萨巴联邦医疗中心艾滋病毒阳性患者中结核病的流行情况。研究设计:本研究采用横断面研究设计,研究在三角洲州Asaba联邦医疗中心就诊的HIV患者中结核分枝杆菌的流行情况。研究地点和持续时间:研究在联邦医学中心进行。数据收集的特定时间段为2022年11月至2023年1月。方法:从已知HIV患者中抽取188份样本。采用随机抽样方法选取患者。采用GeneXpert (GX2.1模型)对样品进行DNA结核分枝杆菌复合体(MTBC)核酸扩增(NAA)和利福平耐药性分析。参与者的人口统计数据通过问卷调查获得。 结果:188份HIV患者样本中,13例(8.7%)患者检出MTB,其中男性6例(12%)最高。MTB以19 ~ 29岁年龄组最为流行。 结论:根据这些数据,结核分枝杆菌在三角洲州Asaba的HIV患者中广泛存在。因此,必须鼓励患者坚持治疗和预防措施。
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Prevalence of Mycobacterium tuberculosis among HIV Patients Attending Federal Medical Centre Asaba, Delta State, Nigeria
Aim: The study aimed to ascertain the prevalence of tuberculosis among HIV-positive patients at the Federal Medical Center Asaba in Delta State, Nigeria. Study Design: This study engaged a cross-sectional study design to prevalence of Mycobacterium Tuberculosis among HIV Patients Attending Federal Medical Centre Asaba, Delta State. Place and Duration of the Study: The study was conducted in Federal Medical Center. Data collection spanned a specific duration from November, 2022 to January, 2023. Methodology: A total of 188 samples were obtained from known HIV patients. The patients were selected by random sampling technique. The samples were analysed using GeneXpert machine (GX2.1 model) with the nuclei acid amplification (NAA) of DNA mycobacterium tuberculosis complex (MTBC) and resistance to rifampicin. Demographic data of participants were obtained through questionnaires. Results: Out of 188 samples from HIV patients analyzed, MTB was detected in 13 (8.7%) patients with the highest prevalence recorded among male subjects 6(12%). Age group 19-29 was the most prevalent of MTB among the test subjects. Conclusion: Mycobacterium tuberculosis is widespread among HIV patients in Asaba, Delta state, according to these data. As a result, patients must be encouraged to adhere to treatment and preventive measures.
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