肉桂皮乙醇提取物牙膏抑制链球菌生长的抑菌效果

IF 0.2 0 HUMANITIES, MULTIDISCIPLINARY Contagion-Journal of Violence Mimesis and Culture Pub Date : 2023-10-31 DOI:10.30829/contagion.v5i4.17798
Syahdiana Waty, Yetti Lusiani, Aminah Br. Saragih
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引用次数: 0

摘要

<div><table cellspacing="0" cellpadding="0" align="left"><tbody><tr><td align="left" valign="top"><p class="Default"><em>链球菌是口腔内的主要细菌之一。这种细菌是导致龋齿的细菌。含氟牙膏对防止蛀牙很重要。使用含氟牙膏造成了一个困境,因为如果使用浓度不达标,它可能会导致氟中毒的副作用。然而,还有一种替代方法,即使用含有精油和植物提取物的牙膏。所使用的研究类型是实验方法。该研究于2023年5月至7月在棉兰卫生部卫生理工学院的制药实验室和北苏门答腊大学医院的微生物实验室进行。本研究的样本是在干预前后使用12.5%肉桂皮乙醇提取物牙膏的30名调查对象的牙菌斑。获得的数据将使用非参数Wilcoxon检验和参数配对t检验进行统计分析。结果表明,肉桂皮乙醇提取物浓度为12.5%的牙膏对链球菌的抑制作用显著,p值为<0.05。这种牙膏能够显著减少所有细菌群中牙菌斑中的细菌菌落数量。希望这些结果能为公众提供信息,说明肉桂皮乙醇提取物可作为牙膏的有效成分。</em></ td></tr></tbody></table></div><strong><;关键词:抗菌,肉桂皮,链球菌,牙膏</em></strong>;
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Antibacterial Effectiveness of Cinnamon Peel Ethanol Extract Toothpaste (Cinnamomum burmanni) In Inhibiting the Growth of Streptococcus Bacteria

Streptococcus is one of the dominant bacteria in the oral cavity. This bacteria is the bacteria that causes dental caries. Toothpaste containing fluoride is important for preventing tooth decay. Using fluoride toothpaste creates a dilemma because it can cause side effects in the form of fluorosis if used in concentrations that are not recommended. However, there is an alternative way, namely by using toothpaste which contains essential oils and plant extracts. The type of research used is the experimental method. The research was conducted at the pharmaceutical laboratory of the Health Polytechnic of the Ministry of Health Medan and the Microbiology laboratory of the University of North Sumatra Hospital, which was carried out from May to July 2023. The samples in this study were dental plaque taken from 30 respondents pre and post intervention application of 12.5% cinnamon bark ethanol extract toothpaste. The data obtained will be analyzed statistically using the non-parametric Wilcoxon test and the parametric Pair T-Test. The results showed that toothpaste with cinnamon bark ethanol extract with a concentration of 12.5% had significant antibacterial activity in inhibiting the growth of Streptococcus bacteria with a p value &lt;0.05. This toothpaste is able to significantly reduce the number of bacterial colonies found in dental plaque in all bacterial groups. It is hoped that these results will provide information to the public that the ethanol extract of cinnamon bark can be used as an active ingredient in toothpaste.

Keywords: Antibacterial, Cinnamon bark, Streptococcus, Toothpaste
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来源期刊
Contagion-Journal of Violence Mimesis and Culture
Contagion-Journal of Violence Mimesis and Culture HUMANITIES, MULTIDISCIPLINARY-
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