An Interesting Case of Sjögren’s Syndrome Presenting with Hypokalemic Quadriparesis and Distal Renal Tubular Acidosis

Abstract Sjögren’s syndrome is well known to masquerade with varied presentations due to its propensity to produce multisystemic and extraglandular disease. We present the case of Sjögren’s syndrome manifesting as new onset, acute quadriparesis. The patient had no articular manifestations suggesting a primary connective tissue disease or obvious sicca symptoms. Laboratory tests revealed severe hypokalemia and metabolic acidosis and antinuclear antibodies profile was positive for anti-Ro/SS-A antibody. Clinical examination revealed long-standing dental caries. A minor salivary gland biopsy showed features of Sjögren’s disease. The patient was started on potassium supplements and immunomodulatory therapy which led to clinical improvement in a week.