治疗类风湿性关节炎的植物

Q4 Pharmacology, Toxicology and Pharmaceutics Journal of Natural Remedies Pub Date : 2023-11-02 DOI:10.18311/jnr/2023/34055
Sweta B. Besh, Maitri Mahant, Divya Kanojiya, Sapana Patil, Rajesh A. Maheshwari
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引用次数: 0

摘要

慢性、持续性和致残的自身免疫性疾病被称为类风湿性关节炎(RA),其特征是关节周围的软骨和骨骼损伤以及关节的全身性炎症。75%的RA患者是女性,这一事实表明激素在该病的病因学中具有重要意义。滑膜炎症涉及遗传、环境、包括免疫变量的机制,这些变量被认为在其致病机制中起作用。当涉及到治疗类风湿性关节炎时,重点已经从缓解症状转移到实施影响疾病活动的治疗方案,并最终被发现可以停止或停止结构性关节破坏。水杨酸盐、非甾体抗炎药(NSAIDs)、皮质类固醇、疾病调节抗风湿药(DMARDs)、甲氨蝶呤(MTX)以及生物反应增强剂都是药物的一些例子。然而,它也有需要克服的负面影响。需要使用草药和各种植物来治疗关节疼痛和炎症。有许多具有药用特性的植物已被临床证明具有抗类风湿关节炎的作用。因此,具有显著益处的植物及其衍生物正被用于类风湿关节炎的治疗。目前的评估主要集中在具有抗类风湿性关节炎功效的药用植物上。
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Plants Used in the Treatment of Rheumatoid Arthritis
Chronic, persistent and incapacitating autoimmune ailments known as Rheumatoid Arthritis (RA) are marked by cartilage and bone damage surrounding the joints as well as systemic inflammation of the joints. The fact that 75% of RA patients are female points to the significance of hormones in the etiology of the condition. Synovial membrane inflammation involves mechanisms in the form of genetic, environmental, including immunologic variables that are believed to have a role in its pathogenic mechanism. When it comes to treating RA, the focus has shifted from relieving symptoms to implementing therapeutic regimens that affect the disease’s activity and eventually have been found to halt or stop structural joint destruction. Salicylates, Non-Steroidal Anti-Inflammatory Drugs (NSAIDs), corticosteroids, and Disease Modifying Anti-Rheumatic Drugs (DMARDs), Methotrexate (MTX), as well as biologic response enhancers, are some examples of drugs. However, it has negative effects which need to be overcome. It is required to employ herbs and a variety of plants to treat joint pain and inflammation. There are numerous plants with medicinal properties that have been clinically demonstrated to have anti-rheumatoid arthritis effects. As a result, plants and their derivatives with significant benefits are being used for the management of rheumatoid arthritis. The current assessment focuses on medicinal plants that have anti-rheumatoid arthritis efficacy.
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来源期刊
Journal of Natural Remedies
Journal of Natural Remedies Pharmacology, Toxicology and Pharmaceutics-Pharmacology
CiteScore
0.40
自引率
0.00%
发文量
27
期刊介绍: Nature can provide all the remedies, for all. All substances produced by nature can be recognized; all cells talk the same language as we all are from the same mother cell. Journal of Natural Remedies is devoted toward the understandings of all remedies from nature. Journal of Natural Remedies publishes original articles related to utilisation of any natural source for remedy including bioactive natural products. Studies related to the resources, chemistry (including analytical), biological activity, biotechnology and pharmacology (including toxicology) of archaea, bacteria, protistas, fungi, plants, animals, viruses and minerals fall within the journal’s scope.
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