一种复方阿育吠陀降压制剂的生药学及植物化学评价[nia / dg /2015/01]

Swati Goyal, Sudipta Kumar Rath
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引用次数: 0

摘要

高血压是一种复杂的临床疾病,在印度城市人口中发病率为40.8%,在农村人口中发病率为17.9%。多种抗高血压药物用于治疗高血压。然而,许多药物有副作用,而且是危险的。NIA/DG/2015/01是一种抗高血压的阿育吠陀中药制剂,含有阿朱那(Terminalia Arjuna Roxb.)、阿什瓦甘达(Withania somnifera Linn.)、加塔曼西(Nardostachys Jatamansi DC.)、香普什皮(Convolvulus pluricaulis Choisy.)、普那纳瓦(Boerhavia diffusa Linn.)。目的:对复方阿育吠陀降压制剂[NIA/DG/2015/01]从生药学、理化、植物化学和色谱等方面进行评价。材料与方法:采用药效学、理化、植物化学和色谱等方法对某复方阿育吠陀降压制剂[NIA/DG/2015/01]进行纯度、安全性和质量评价。观察与结果:药效学、理化、植物化学和色谱结果均在正常范围内。结论:该复方阿育吠陀降压制剂[NIA/DG/2015/01]纯度、安全性、真实性均符合质量标准。
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PHARMACOGNOSTICAL AND PHYTOCHEMICAL EVALUATION OF A POLYHERBAL ANTIHYPERTENSIVE AYURVEDIC FORMULATION [NIA/DG/2015/01]
Introduction: Hypertension is a complex clinical illness with a frequency of 40.8 percent in the urban Indian population and 17.9 percent in the rural population. Multiple antihypertensives are used to treat hypertension. However, many have adverse effects and are hazardous. NIA/DG/2015/01 is a polyherbal antihypertensive ayurvedic ghan formulation, containing Arjuna (Terminalia arjuna Roxb.), Ashwagandha (Withania somnifera Linn.), Jatamansi (Nardostachys jatamansi DC.), Shankhpushpi (Convolvulus pluricaulis Choisy.), Punarnava (Boerhavia diffusa Linn.). Aim and objective: To evaluate a polyherbal antihypertensive Ayurvedic formulation [NIA/DG/2015/01] in terms of pharmacognosy, physiochemistry, phytochemistry and chromatography. Materials and methods: A polyherbal antihypertensive ayurvedic formulation [NIA/DG/2015/01] was evaluated for purity, safety, and quality using pharmaco-gnostical, physiochemical, phytochemical, and chromatographic methods. Observations and Results: The pharmaco-gnostical, physiochemical, phytochemical, and chromatographic results were within normal limits per API. Conclusion: The present sample of a polyherbal antihypertensive ayurvedic formulation [NIA/DG/2015/01] met quality standards for purity, safety and authenticity.
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