一项比较研究,评估haritaki choornam与madhu和生活方式改变对血清总胆固醇水平的影响

Sneha P. Thomas, Sajitha Bhadran, Smitha Mary Shine
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摘要

印度的血脂异常患病率非常高(79%),这需要紧急干预策略来预防和管理这一关键的心血管危险因素。本研究旨在探讨Haritaki choornam联合madhu和生活方式改变对血清总胆固醇水平的影响。高血清总胆固醇可通过kaphamedohara、deepana、rookshana和lekhana药物恢复正常。Haritaki (Terminalia chebula Retz.)和madhu(蜂蜜)具有上述所有特性。我们对60名符合纳入和排除标准的男女受试者进行了介入前和介入后研究。将30名受试者随机分为干预组(1组)和对照组(2组),实验组早晚餐后分别服用3克Haritaki choornam和6克madhu,同时改变生活方式45天,对照组仅改变生活方式45天。经统计分析,服用Haritaki choornam并改变生活方式的研究组血清总胆固醇的下降幅度大于单独改变生活方式的对照组。结果分别采用组内配对t检验和组间独立t检验进行统计学分析。血清总胆固醇差异有统计学意义(p值)。
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A COMPARATIVE STUDY TO ASSESS THE EFFECT OF HARITAKI CHOORNAM WITH MADHU AND LIFESTYLE MODIFICATIONS ON SERUM TOTAL CHOLESTEROL LEVEL
The prevalence of dyslipidemia is very high in India (79%), which requires urgent intervention strategies to prevent and manage this critical cardiovascular risk factor. This study aimed to explore the efficacy of Haritaki choornam with madhu and lifestyle modification on serum total cholesterol levels. Elevated serum total cholesterol can be returned to normal by kaphamedohara, deepana, rookshana and lekhana drugs. Haritaki (Terminalia chebula Retz.) and madhu (honey) have all the mentioned properties. A pre and post-interventional study was conducted in 60 subjects of both sexes, satisfying inclusion and exclusion criteria. Thirty subjects were randomly allocated to the Intervention group (Group 1) and comparison group (Group 2). The study group received 3 gm. of Haritaki choornam with 6 gm. of madhu as anupama after food in the morning and evening, along with lifestyle modifications for 45 days, while the comparison group kept on lifestyle modifications only for 45 days. On statistical analysis, the reduction in serum total cholesterol in the study group taking Haritaki choornam with madhu and lifestyle modifications is more than in the comparison group who were kept on lifestyle modifications alone. The results were analysed statistically using paired t-tests and independent t-tests within the group and between groups, respectively. The serum total cholesterol was statistically significant with a p-value.
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