低磁场作用下生物效应的自由基对机制及其验证方法

Jin-hua Ouyang
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引用次数: 0

摘要

低磁场的生物效应是一个非常重要的研究课题,它不仅适用于航天飞行和空间站生活,也适用于地下掩体等一些地面磁屏蔽条件。然而,据我所知,与HMF生物效应相关的机制尚不清楚。在本研究中,我首先在现有研究的基础上总结了一种羟甲基糠醛生物效应的自由基对机制,然后提出如何通过实验证明自由基对机制在羟甲基糠醛生物效应中的真实性。如何证明激进的配对机制的真理我给激进的单线态收益率之间的关系对和羟甲基糠醛的角度描述取向的基础超精细张量与电子自旋和原子核自旋是可能的一对激进机制一方面,并给出关键方法是通过角变化导致生物效应体内或体外证明或否定另一方面,机制因为HMF的生物效应可能与这个角度有关,这在实验中很容易控制。
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The radical pair mechanism of biological effects on hypomagnetic fields and one method to verify it
The biological effects due to a hypomagnetic field (HMF) is a very important subject not only for aerospace traveling and space station living but also for some magnetic shielding conditions on the ground just like the underground bunkers and etc. However, to my knowledge, the mechanisms which can be related to the biological effects of a HMF remain unclear. In this study, I firstly summary one radical pair mechanism of biological effects on a HMF based on present researches, and then propose how to prove the radical pair mechanism’s truth in biological effects on a HMF through experiments. In the way of how to prove the radical pair mechanism’s truth I give the relation between the singlet yield of the radical pair and the angle describing the orientation of a HMF to the basis of the hyperfine tensor related to the electron spin and the nuclei spin is the possible one radical pair mechanism on one hand, and give the crucial method which is through that angle changed causes the biological effects in vivo or vitro to prove or disprove the mechanism on the other hand, because the biological effects of a HMF can be related with that angle, which is very easy to be controlled in experiments.
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