设计、完善和反思澳大利亚COVID-19全国活体指南的3年每日证据监测

Steve McDonald, Tari Turner
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摘要

澳大利亚于2020年4月发布了《2019冠状病毒病国家生活指南》,其中包括200多项指导COVID-19患者临床护理的建议。在该指南于2023年8月退役之前,通过日常监测不断监测新的证据。本文描述了证据监测是如何建立的(当时整理新型冠状病毒信息的工作还处于起步阶段,而且往往是重复的),以及它在大流行期间是如何演变的。在监测的广泛来源中,来自领先医学期刊、medRxiv预印本和PubMed自动警报的COVID-19研究集合证明,在识别时间关键和有影响力的证据方面最持久。本文还探讨了如何通过使用消息应用程序和通信平台跟踪证据并将监视整合到整个证据工作流程中。有几个因素促成了每日监测的可行性,包括准则的明确界定范围;集中精力发挥最大影响;通过与他人合作,尽量减少重复;建立简单有效的证据管理程序;以及从一开始人员持续参与的价值。澳大利亚新冠肺炎生活指南的例子证明了日常证据监测在维持3年多新冠肺炎生活指南方面的可行性和重要作用。
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Designing, refining and reflecting on 3 years of daily evidence surveillance for Australia's living national COVID-19 guidelines
Australia’s national living guidelines for COVID-19 were launched in April 2020 and include over 200 recommendations to guide the clinical care of patients with COVID-19. Until the guidelines were retired in August 2023, new evidence was continually monitored through daily surveillance. This paper describes how evidence surveillance was established (at a time when efforts to collate information on the novel coronavirus were in their infancy and often duplicative) and how it evolved throughout the pandemic. Among the wide range of sources monitored, the collections of COVID-19 research from leading medical journals, medRxiv preprints and PubMed auto alerts proved the most enduring in identifying time-critical and impactful evidence. The paper also explores how evidence was tracked and surveillance integrated into the overall evidence workflow by using messaging apps and communication platforms. Several factors contributed to the feasibility of daily surveillance, including the clearly defined scope of the guidelines; focusing efforts on maximum impact; minimising duplication by partnering with others; setting up simple but effective processes for managing evidence; and the value of continuous involvement of personnel from the outset. The example of Australia’s living COVID-19 guidelines has demonstrated the feasibility and essential role of daily evidence surveillance in maintaining COVID-19 living guidelines for over 3 years.
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