Lingmin Jiang, Ho Le Han, Yuxin Peng, Doeun Jeon, Donghyun Cho, Cha Young Kim, Jiyoung Lee
{"title":"内生新杆菌BRMEA1T耐热适应性的基因组研究","authors":"Lingmin Jiang, Ho Le Han, Yuxin Peng, Doeun Jeon, Donghyun Cho, Cha Young Kim, Jiyoung Lee","doi":"10.5423/rpd.2023.29.3.321","DOIUrl":null,"url":null,"abstract":"The bacterium <i>Neobacillus endophyticus</i> BRMEA1<sup>T</sup>, isolated from the medicinal plant <i>Selaginella involvens</i>, known as its thermotolerant can grow at 50°C. To explore the genetic basis for its heat tolerance response and its potential for producing valuable natural compounds, the genomes of two thermotolerant and four mesophilic strains in the genus <i>Neobacillus</i> were analyzed using a bioinformatic software platform. The whole genome was annotated using RAST SEED and OrthVenn2, with a focus on identifying potential heattolerance- related genes. <i>N. endophyticus</i> BRMEA1<sup>T</sup> was found to possess more stress response genes compared to other mesophilic members of the genus, and it was the only strain that had genes for the synthesis of osmoregulated periplasmic glucans. This study sheds light on the potential value of <i>N. endophyticus</i> BRMEA1<sup>T</sup>, as it reveals the mechanism of heat resistance and the application of secondary metabolites produced by this bacterium through whole-genome sequencing and comparative analysis.","PeriodicalId":36349,"journal":{"name":"Research in Plant Disease","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Genome-Based Insights into the Thermotolerant Adaptations of Neobacillus endophyticus BRMEA1T\",\"authors\":\"Lingmin Jiang, Ho Le Han, Yuxin Peng, Doeun Jeon, Donghyun Cho, Cha Young Kim, Jiyoung Lee\",\"doi\":\"10.5423/rpd.2023.29.3.321\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The bacterium <i>Neobacillus endophyticus</i> BRMEA1<sup>T</sup>, isolated from the medicinal plant <i>Selaginella involvens</i>, known as its thermotolerant can grow at 50°C. To explore the genetic basis for its heat tolerance response and its potential for producing valuable natural compounds, the genomes of two thermotolerant and four mesophilic strains in the genus <i>Neobacillus</i> were analyzed using a bioinformatic software platform. The whole genome was annotated using RAST SEED and OrthVenn2, with a focus on identifying potential heattolerance- related genes. <i>N. endophyticus</i> BRMEA1<sup>T</sup> was found to possess more stress response genes compared to other mesophilic members of the genus, and it was the only strain that had genes for the synthesis of osmoregulated periplasmic glucans. This study sheds light on the potential value of <i>N. endophyticus</i> BRMEA1<sup>T</sup>, as it reveals the mechanism of heat resistance and the application of secondary metabolites produced by this bacterium through whole-genome sequencing and comparative analysis.\",\"PeriodicalId\":36349,\"journal\":{\"name\":\"Research in Plant Disease\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-09-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Research in Plant Disease\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.5423/rpd.2023.29.3.321\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"Agricultural and Biological Sciences\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Research in Plant Disease","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5423/rpd.2023.29.3.321","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Agricultural and Biological Sciences","Score":null,"Total":0}
Genome-Based Insights into the Thermotolerant Adaptations of Neobacillus endophyticus BRMEA1T
The bacterium Neobacillus endophyticus BRMEA1T, isolated from the medicinal plant Selaginella involvens, known as its thermotolerant can grow at 50°C. To explore the genetic basis for its heat tolerance response and its potential for producing valuable natural compounds, the genomes of two thermotolerant and four mesophilic strains in the genus Neobacillus were analyzed using a bioinformatic software platform. The whole genome was annotated using RAST SEED and OrthVenn2, with a focus on identifying potential heattolerance- related genes. N. endophyticus BRMEA1T was found to possess more stress response genes compared to other mesophilic members of the genus, and it was the only strain that had genes for the synthesis of osmoregulated periplasmic glucans. This study sheds light on the potential value of N. endophyticus BRMEA1T, as it reveals the mechanism of heat resistance and the application of secondary metabolites produced by this bacterium through whole-genome sequencing and comparative analysis.
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
