支架植入术后打鼾对颈动脉血流动力学的影响:振荡的作用

IF 0.8 4区 医学 Q4 BIOPHYSICS Acta of bioengineering and biomechanics Pub Date : 2023-01-01 DOI:10.37190/abb-02207-2023-02
None Xianghao Zhang, None Zhenmin Fan, None Xiao Liu, None Mingyuan Liu, None Xia Ye, None Xiaoyan Deng
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引用次数: 0

摘要

目的:超重及高龄患者行血管内支架植入术时,常见打鼾。研究证明打鼾与颈动脉狭窄之间存在相关性,因此颈动脉支架植入术后打鼾可能会促进或恶化临床表现。方法构建患者颈动脉分岔模型,数值分析不同打鼾状态下颈动脉血流动力学变化,验证上述假设。这些条件包括小振幅和大振幅、低频和高频以及不同年龄组。结果发现,高幅度鼾症抑制了支架段血流紊乱,而ICA下游区域变得更加混乱,导致支架内内膜再狭窄和血栓形成。此外,有打鼾症状的老年人局部血流模式更容易因低速血流而改变,增加血管重构和血栓形成的可能性。此外,打鼾频率的增加对局部扰动流几乎没有影响。结论老年人高幅鼾置入术后应尽早积极接受药物治疗,避免潜在不良事件的发生。
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Hemodynamic Impact of Snoring on Carotid Artery after Stent Implantation: The Role of Oscillation
Purpose Snoring is common in overweight and old patients treated by endovascular stenting. Studies have proved a correlation between snoring and carotid stenosis, thus, snoring after carotid artery stenting (CAS) might promote or worsen clinical performance. Methods This study tested this hypothesis by constructing a patient-specific carotid bifurcation model and numerically analyzing hemodynamic changes of the carotid artery under different snoring conditions. These conditions included small and large amplitude, low and high frequency, and different age groups. Results The results found that high amplitude snoring suppressed the disturbed flow at the stented segment, while the downstream region of ICA became more chaotic, accounting for in-stent intimal restenosis and thrombosis. Furthermore, local blood flow patterns of elder groups with snoring symptoms were more likely to be changed due to low-speed flow, increasing the possibility of vascular remodeling and thrombosis. Besides, increased snoring frequency hardly influenced the local disturbed flow. Conclusions Therefore, older adults should receive medical treatment actively after stenting for high amplitude snoring as soon as possible to avoid potential adverse events.
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来源期刊
Acta of bioengineering and biomechanics
Acta of bioengineering and biomechanics BIOPHYSICS-ENGINEERING, BIOMEDICAL
CiteScore
2.10
自引率
10.00%
发文量
0
期刊介绍: Acta of Bioengineering and Biomechanics is a platform allowing presentation of investigations results, exchange of ideas and experiences among researchers with technical and medical background. Papers published in Acta of Bioengineering and Biomechanics may cover a wide range of topics in biomechanics, including, but not limited to: Tissue Biomechanics, Orthopedic Biomechanics, Biomaterials, Sport Biomechanics.
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