[对伴随老化的流量体积曲线的影响——重点关注其变化与FEV1.0%的关系]。

H Muraki
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引用次数: 0

摘要

比较呼吸功能的变化。所得结果如下:选取462名呼吸和循环系统无疾病的正常健康男性成人,测定1秒用力呼气量(FEV1.0%)和峰值流量(PF)、75%用力呼气量(V75)、50%用力呼气量(V50)和25%用力呼气量(V25)。1. 结果各测量值FEV1.0%、PF、V75、V50、V25随年龄增长而降低。V50/V25随年龄增大而增大,FEV1.0%和V25的最小值和最大值分别为6.86和36.46。2. FEV1.0%与V50/V25的关系。FEV1.0%与V50/V25之间的关系直到34年才有显著性变化。个体差异发生在35 - 39岁年龄组。这一潮流在40到49岁的人群中很出名。但在50岁以上的人群中没有发现个体差异。提示衰老不仅影响大气道,也影响小气道,并伴有外周气道阻力增大,呼气流量减小
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[Effects on flow volume curve accompanied by aging--with emphasis on the relation between the change and FEV1.0%].

Changes in respiratory function were compared. The results obtained were as follows. Subjects selected were 462 normal healthy male adults with no disorders in respiratory and circulatory systems, of whom forced expiratory volume in 1 second (FEV1.0%) and peak flow (PF), forced expiratory volume in 75% (V75), forced expiratory volume in 50% (V50) and forced expiratory volume in 25% (V25) were determined. 1. Results of each measured value FEV1.0%, PF, V75, V50 and V25 decreased with age. But V50/V25 increased with age Minimum and maximum values were 6.86 and 36.46 in FEV1.0% and V25. 2. Relationship between FEV1.0% and V50/V25. Both FEV1.0% and V50/V25 did not show marked relation till 34 years. Individual variation occurs in 35 to 39 year old group. This current was famous in 40 to 49 year old group. But no individual variations were found over 50 year old. This suggested that aging affects not only large airways but also small airways, and which is accompanied with enlarged peripheral air way resistance and decreased expiratory flow volume

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