女性生殖器疱疹的现代治疗方法

L.B. Markin, O.O. Matviіenko, O.O. Korytko, K.L. Shatylovych
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引用次数: 0

摘要

生殖器疱疹(GH)是由单纯疱疹病毒(HSV)引起的一种常见的性传播疾病。它的特点是终身感染和周期性再激活。直到最近,生长激素更多地是由2型HSV (HSV-2)引起的,但现在,1型HSV (HSV-1)感染病例非常常见,在一些国家甚至比2型HSV更常见。目前世界上有4亿多人患有2型单纯疱疹病毒引起的生长激素。在美国,近五分之一的成年人(约4000万人)感染了2型单纯疱疹病毒。每年约有100万新感染病例。最近,人们对妇女生长激素治疗的新方法给予了很大的关注。这个问题非常紧迫,因为这种感染在世界上非常普遍。GH的主要病因是HSV-1和HSV-2。治疗生长激素的方法因病毒类型(HSV-1或HSV-2)以及有无临床表现而异。对文献资料的分析表明,生长激素的治疗有两种方式:一种是间歇性抗病毒治疗,即患者在生长激素复发期间接受短期抗病毒治疗;另一种是抑制性抗病毒治疗,即患者每天服用药物以防止复发。我们的临床经验使我们能够推荐乌克兰药物Virostat(制造商“基辅维生素厂”)用于治疗妇女HSV感染。用病毒抑制剂治疗的方案取决于这些是感染的首次表现还是复发。目前还没有批准用于治疗和预防生长激素的疫苗,因此,积极预防和早期诊断可以增加不同年龄组和不同疾病阶段妇女安全有效治疗生长激素的机会。
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Modern approaches to the therapy of genital herpes in women
Genital herpes (GH) is a common sexually transmitted disease caused by the herpes simplex virus (HSV). It is characterized by lifelong infection and periodic reactivation. Until recently, GH was more often caused by HSV type 2 (HSV-2), but now it very common infection cases by HSV type 1 (HSV-1) and in some countries are even more common than HSV-2. More than 400 million people currently have GH caused by HSV-2 in the world. In the United States nearly one in five adults (approximately 40 million people) are infected with HSV-2. About 1 million new infections occur every year.Recently, much attention has been paid to the issue of new approaches to GH therapy in women. The problem is extremely urgent, since this infection is very common in the world. The main causes of GH are HSV-1 and HSV-2.Approaches to the treatment of GH differ depending on the type of virus (HSV-1 or HSV-2), as well as the absence or presence of clinical manifestations. The analysis of literature data shows that is there are two ways of GH treatment: episodic antiviral therapy, when patients undergo short courses of antiviral therapy during GH relapse, or suppressive antiviral therapy, when patients take medication daily to prevent relapses.Our clinical experience allows us to recommend the ukrainian drug Virostat (manufacturer “Kyiv Vitamin Plant”) for the treatment of HSV infection in women. The scheme of treatment with the Virostat depends on whether these are the first manifestations of infection or its recurrence.There are no approved vaccines for the treatment and prevention of GH, therefore, active prevention and early diagnosis increase the chances of safe and effective treatment of GH in women of different age groups and at different stages of the disease.
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来源期刊
Reproductive Endocrinology
Reproductive Endocrinology Medicine-Obstetrics and Gynecology
CiteScore
0.50
自引率
0.00%
发文量
13
审稿时长
8 weeks
期刊最新文献
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