生物陶瓷材料和有色光照射对衰老大鼠学习记忆的影响。

IF 1.4 4区 医学 Q4 GERIATRICS & GERONTOLOGY Experimental Aging Research Pub Date : 2023-11-16 DOI:10.1080/0361073X.2023.2278983
Ting-Kai Leung, Yu-Chen Chen, Ming-Wei Chao, Chia-Yi Tseng
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引用次数: 0

摘要

衰老的特征是自由基的分子损伤,导致神经功能障碍和记忆障碍。本研究探讨了生物陶瓷材料和彩色光对老年大鼠神经退行性症状的缓解作用。我们采用Morris水迷宫、新型物体识别和开放场试验来评估不同颜色光谱对d -半乳糖诱导的衰老大鼠的影响。研究结果表明,具有不同波长光的生物陶瓷材料可以改善衰老大鼠的活动、识别和记忆。在开放领域和新的目标识别测试中观察到显著的增强,并且在Morris水迷宫中有改善的趋势。这些作用归因于生物陶瓷材料的抗氧化性能和微循环增强。颜色刺激可能影响酶、人体生理、心理活动和自主神经系统。本研究强调了探索老年大鼠神经退行性症状和记忆缺陷的新干预措施的意义。结果表明,具有不同颜色光谱的生物陶瓷材料对认知功能有积极影响。这些发现有助于我们了解生物陶瓷材料的治疗潜力,并强调了在这一领域进一步研究的必要性。
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Effects of Bioceramic Material and Colored Light Irradiation on Learning and Memory in Aging Rats.

Aging is characterized by molecular damage from free radicals, leading to neural dysfunction and memory impairment. This study investigated using bioceramic material and colored light to mitigate neurodegenerative symptoms in aging rats. We assessed the effects of different color light spectrums on D-galactose-induced aging rats using the Morris water maze, novel object recognition, and open field tests. Findings revealed that bioceramic material with various light wavelengths improved activity, recognition, and memory in aging rats. Significant enhancements were observed in the open field and novel object recognition tests, with a trend toward improvement in the Morris water maze. These effects are attributed to the antioxidant properties and microcirculation enhancement associated with bioceramic materials. Color stimulation may impact enzymes, human physiology, psychological activity, and the autonomic nervous system. This study highlights the significance of exploring novel interventions for neurodegenerative symptoms and memory deficits in aging rats. Results indicate that bioceramic material with different colored light spectrums positively influences cognitive function. These findings contribute to our understanding of the therapeutic potential of bioceramic materials and emphasize the need for further research in this area.

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来源期刊
Experimental Aging Research
Experimental Aging Research 医学-老年医学
CiteScore
3.60
自引率
0.00%
发文量
68
审稿时长
>12 weeks
期刊介绍: Experimental Aging Research is a life span developmental and aging journal dealing with research on the aging process from a psychological and psychobiological perspective. It meets the need for a scholarly journal with refereed scientific papers dealing with age differences and age changes at any point in the adult life span. Areas of major focus include experimental psychology, neuropsychology, psychobiology, work research, ergonomics, and behavioral medicine. Original research, book reviews, monographs, and papers covering special topics are published.
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