{"title":"NaF和CaF2对大鼠胃粘膜影响的比较。一种光学、扫描和透射电子显微镜的研究。","authors":"P Kertész, T Kerényi, J Kulka, J Bánóczy","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>Rat stomachs were studied after intragastrically administered, repeated doses of 0.1 N HCl, 100 mmol/l NaF, 50 mmol/l CaF2 in 0.1 N HCl, respectively. NaF produced extensive desquamation and cell injury, while CaF2 caused some desquamation and a slight decrease in secretory activity as revealed by light microscopic, SEM and TEM examinations.</p>","PeriodicalId":76971,"journal":{"name":"Acta morphologica Hungarica","volume":"37 1-2","pages":"21-8"},"PeriodicalIF":0.0000,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Comparison of the effects of NaF and CaF2 on rat gastric mucosa. A light-, scanning- and transmission electron microscopic study.\",\"authors\":\"P Kertész, T Kerényi, J Kulka, J Bánóczy\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Rat stomachs were studied after intragastrically administered, repeated doses of 0.1 N HCl, 100 mmol/l NaF, 50 mmol/l CaF2 in 0.1 N HCl, respectively. NaF produced extensive desquamation and cell injury, while CaF2 caused some desquamation and a slight decrease in secretory activity as revealed by light microscopic, SEM and TEM examinations.</p>\",\"PeriodicalId\":76971,\"journal\":{\"name\":\"Acta morphologica Hungarica\",\"volume\":\"37 1-2\",\"pages\":\"21-8\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1989-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Acta morphologica Hungarica\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Acta morphologica Hungarica","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
以0.1 N HCl、100 mmol/l NaF、50 mmol/l CaF2等高剂量0.1 N HCl反复灌胃后,对大鼠胃进行研究。光镜、扫描电镜和透射电镜检查显示,NaF引起广泛的脱屑和细胞损伤,而CaF2引起部分脱屑和分泌活性轻微下降。
Comparison of the effects of NaF and CaF2 on rat gastric mucosa. A light-, scanning- and transmission electron microscopic study.
Rat stomachs were studied after intragastrically administered, repeated doses of 0.1 N HCl, 100 mmol/l NaF, 50 mmol/l CaF2 in 0.1 N HCl, respectively. NaF produced extensive desquamation and cell injury, while CaF2 caused some desquamation and a slight decrease in secretory activity as revealed by light microscopic, SEM and TEM examinations.