巴西新生儿筛查试验:流行率与区域和社会经济不平等

Mariana B. Mallmann , Yaná T. Tomasi , Antonio Fernando Boing
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摘要

目的确定巴西格思里试验、听力和红色反射筛查试验的患病率及其相关因素。方法:这是一项基于人群的横断面研究,分析了参与2013年全国健康调查的5231名2岁以下儿童的数据。该研究描述了在任何时期进行的三种新生儿筛查试验的流行率和置信区间(95% CI),以及它们与国家地区、肤色/种族、私人医疗保险和人均家庭收入的关系。采用Logistic回归模型,结合样本权重计算比值比。结果巴西各年龄段Guthrie试验筛查率为96.5%,新生儿听力筛查率为65.8%,红色反射筛查率为60.4%。在母亲/监护人报告的人均家庭收入较高、居住在南部和东南部地区以及拥有私人医疗保险的儿童中,三项筛查测试的表现明显较高(p <0.001)。根据肤色/种族的不同,测试的表现没有统计学上的显著差异(p >0.05)。在建议的期间进行测试时,也证实了同样的不平等现象,而且社会经济梯度很大。结论:全国新生儿筛查试验的执行情况存在不平等,在政府指导方针规定的期间内,这些试验的执行情况也存在不平等。在巴西这样的全民公共卫生系统中保证这些检测的执行,应促进公平并使所有人都能获得检测。
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Neonatal screening tests in Brazil: prevalence rates and regional and socioeconomic inequalities

Objective

To identify the prevalence and associated factors with the performance of the Guthrie test, hearing, and red reflex screening tests in Brazil.

Methods

This was a population‐based, cross‐sectional study that analyzed data on 5,231 children under 2 years of age participating in the National Health Survey of 2013. The study described the prevalence and Confidence Intervals (95% CI) of the three neonatal screening tests performed, in any period, and their association with the country's regions, skin color/ethnicity, private health insurance, and per capita household income. Logistic regression models were used, and odds ratios were calculated by incorporating sample weights.

Results

The prevalence of Guthrie test screening in Brazil at any time of life was 96.5%, that of the newborn hearing screening was 65.8% and that of the red reflex screening test was 60.4%. The performance of the three screening tests was significantly higher among children whose mothers/guardians reported higher per capita household income, who lived in the South and Southeast regions, and who had private health insurance (p < 0.001). There was no statistically significant difference regarding the performance of the tests according to skin color/ethnicity (p > 0.05). The same inequalities were verified when the tests were performed during the recommended periods, with a strong socioeconomic gradient.

Conclusions

There are inequalities in the performance of neonatal screening tests in the country, and also in the performance of these tests during the periods established in the governmental guidelines. The guarantee of the performance of these tests in a universal and public health system, as in Brazil, should promote equity and access to the entire population.

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