[排泄管结扎后外分泌胰腺结构变化的形态发生]。

R Rohrbeck, C M Rohrbeck, H P Putzke, L Jonas, R Reding
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引用次数: 0

摘要

未标记:我们观察了51只Wistar大鼠结扎排泄管后外分泌胰腺的变化。在起源的导管样结构中进行了上皮细胞的定性微测定。结论:腺泡上皮细胞先萎缩后坏死。未见去分化的腺泡细胞萎缩并蜕变为导管样细胞。增殖和增殖前事件发生在导管上皮细胞。囊性导管样结构起源于此。这些未成熟的、很少分化的多能上皮细胞填满了以前的腺泡区,这些上皮细胞看起来与胚胎胰腺细胞相似。
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[The morphogenesis of the structural changes of the exocrine pancreas after ligation of the excretory duct].

Unlabelled: The changes in the exocrine pancreas were investigated after ligature of the excretory duct in 51 Wistar rats. A qualitative microdetermination of the epithelial cells was carried out in the originated ductulus-like structures.

Conclusions: The acinic epithelial cells grow atrophically first of all and become necrotic in the end. A dedifferentiated acinic cellular atrophy with metamorphosis to a ductulus-like cell type could not be observed. Proliferative and preproliferative events occur in the duct epithelial cells. Cystic ductulus-like structures originated from this. These fill out the former acinic areas by immature, few differentiated, pluripotent epithelial cells that look similar to embryonal pancreatic cells.

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