尿道成形术中勃起功能的最佳方法是切除吻合术还是颊粘膜移植尿道成形术?

R. Uğur, A. Şimşek
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摘要

摘要:本研究的目的是评价和比较球尿道狭窄切除术和一期吻合尿道成形术(EPAU)和颊粘膜移植尿道成形术(BMGU)后的勃起功能(EF)。方法:对行尿道成形术的患者进行回顾性分析。纳入研究的标准确定为18岁以上,70岁以下,性活跃。排除标准是;术前严重勃起功能障碍,球外尿道狭窄,心理社会不适应,尿道狭窄伴骨盆骨折,随访时间少于一年。作为主要终点,国际勃起功能指数-5 (IIEF-5)被确定为术前与术后第3、6和12个月的勃起功能指数的比较。次要终点是评估人口统计数据、结构和治疗特征对EF的影响。结果:根据纳入/排除标准确定了50例患者。观察到EPAU患者30例,BMGU患者20例。术后第3个月,EPAU组EF下降有统计学意义。在两组患者中,观察到EF手术后的早期负面影响在第六个月开始改善,并在第一年恢复到基线水平。结论:EPAU技术和BMGU技术对EF的中长期疗效相似。这两种方法都可以在适当的患者群体中安全有效地使用。
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The best method for erection function in urethroplasty; is excision and primary anastomosis or buccal mucosal graft urethroplasty?

Introduction

The aim of this study is to evaluate and compare erection function (EF) after Excision and Primary Anastomosis Urethroplasty (EPAU) and Buccal Mucosal Graft Urethroplasty (BMGU) in bulbar urethral stricture.

Methods

Patients who underwent urethroplasty were identified retrospectively. The criteria for inclusion in the study were determined as being over 18 years old and under 70 years old, being sexually active. Exclusion criteria are; preoperative severe erectile dysfunction, stricture outside the bulbar urethra, psychosocial incompatibility, urethral stricture related to pelvic fracture, follow-up time less than a year. As the primary endpoint, the International Index of Erectile Function-5 (IIEF-5) was determined as a comparison of EF in the preoperative and third, sixth and twelfth months after surgery. The secondary endpoint was the evaluation of the effects of demographic data, stricture and treatment characteristics on EF.

Results

Fifty patients were identified considering the inclusion/exclusion criteria. It was observed that there were 30 patients who underwent EPAU and 20 patients who underwent BMGU. At the third month after surgery, EF showed a statistically significant decrease in the EPAU group. In both patient groups, it was observed that the early negative effects after the operation in EF started to improve in the sixth month and returned to the baseline level by the first year.

Conclusion

EPAU and BMGU techniques have a similar effect on EF in the medium and long term. Both methods can be used safely and effectively in the appropriate patient group.

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