[性腺外生殖细胞肿瘤]。

Morphologiai es igazsagugyi orvosi szemle Pub Date : 1989-07-01

F Baranyay, F Brittig, T Magyarlaki, A Páalvölgyi

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引用次数: 0

摘要

作者描述了两个纵隔(精原细胞瘤和卵黄袋)和一个松果体混合性(精原细胞瘤和卵黄袋)肿瘤的临床病理和免疫组织化学结果。在纵隔黄囊肿瘤中，细胞成分的光镜图像，甲胎蛋白(AFP)，血红蛋白F (Hgb F)，血型抗原，癌胚抗原(CEA)，消化后(神经氨酸酶)花生抗原(neu-PNA)阳性提示肝脏和肠道分化。在某些纵隔精原细胞瘤中，葡萄糖和甘露糖结合的豆蛋白A (Con A)表现出反应。在松果体区混合肿瘤中，除了AFP阳性细胞系外，一些细胞群与针对阶段特异性胚胎抗原1 (SSEA1)的Leu-M1 (CD15)单克隆抗体反应。

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[Extra-gonadal germ-cell tumors].

Authors describe the clinico-pathological and immunohistochemical findings of two mediastinal (seminoma and yolk-sack) and a pineal mixed (seminoma and yolk-sack) tumours. In the mediastinal yolk-sack tumour the light microscopic picture of cellular components, alpha-fetoprotein (AFP), haemoglobin F (Hgb F), blood group antigen, carcinoembryonal antigen (CEA), post-digestion (neuraminidase) peanut antigen (neu-PNA) positivities suggest hepatic and intestinal differentiation. In some cells of mediastinal seminoma the glucose- and mannose-binding concanavalin-A (Con A) showed reaction. In the mixed tumour of the pineal region in addition to AFP positive cell cords some cell groups reacted with Leu-M1 (CD15) monoclonal antibodies raised against stage specific embryonic antigen 1 (SSEA1).

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Morphologiai es igazsagugyi orvosi szemle

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