衡量非洲综合实验室培训中心在22个总统艾滋病紧急救援计划支持国家提供的实验室生物安全方案的培训效果(2008-2014年)。

IF 3.6 Q1 TROPICAL MEDICINE Tropical Medicine and Health Pub Date : 2023-11-21 DOI:10.1186/s41182-023-00557-1
Ritu Shrivastava, Thomas Stevens, Larry Westerman, David Bressler, Elsie van Schalkwyk, Cristina Bressler, Ken Ugwu, Christina Mwangi, Joel Peter Opio, Joseph Nkodyo, Jane W Mwangi, Monte D Martin, Shanna Nesby-O'Dell
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引用次数: 0

摘要

简介:位于南非约翰内斯堡的非洲综合实验室培训中心(ACILT)提供了一个实验室生物安全项目,以便在22个得到总统艾滋病紧急救援计划(PEPFAR)支持的国家改进实验室生物安全做法。这份手稿评估了新获得的知识和技能转移到参与者的工作场所的艾滋病毒和结核病诊断实验室方案。它也是先前出版的手稿的后续,该手稿衡量了ACILT提供的所有课程的培训效果。方法:ACILT举办了20期(2008-2014)实验室生物安全与基础设施课程(又称生物安全课程/包含14个核心实验室安全要素的课程),共22个国家402人参加。2015年,参与者收到了22个电子问题,分为四类:(1)安全政策,(2)管理层参与,(3)安全计划和(4)安全实践评估,以回顾性地确定他们参加课程前后6个月的生物安全实践培训效果。我们使用Kirkpatrick模型来评估知识、技能和阻碍因素的转移。结果:20%(81/402)的参与者完成了电子问卷。表明实施了新的安全措施的积极答复的总体百分比从50%增加到84%。参加课程后,所有四个类别都有所改善,其中安全政策(67% -94%)和安全计划(43% -91%)的增幅最大。创建安全委员会、分配资源和建立设施安全政策是实施和维护实验室安全实践的重要驱动因素。此外,认可的实验室和有国家安全法规或政策的国家有更高的改进百分比。报告最多的挑战是资金不足和缺乏管理执法。结论:总统防治艾滋病紧急救援计划和其他合作伙伴对ACILT等培训机构的投资,有效地建立了可持续的国家自主权,加强了生物安全实践,并被用于抗击人畜共患疾病和COVID-19。虽然在国家/区域一级继续提供支持,但目前还缺乏一种标准化、协调和全大陆范围的可持续方法来提供类似ACILT的生物安全规划。持续提供类似ACILT的生物安全项目有助于持续加强实验室生物安全、质量管理体系和大流行防范。
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Measuring training effectiveness of laboratory biosafety program offered at African Center for Integrated Laboratory Training in 22 President's Emergency Plan for AIDS Relief supported countries (2008-2014).

Introduction: The African Center for Integrated Laboratory Training (ACILT) in Johannesburg, South Africa offered a laboratory biosafety program to improve laboratory biosafety practices in 22 President's Emergency Plan for AIDS Relief (PEPFAR) supported countries. This manuscript evaluates the transference of newly gained knowledge and skills to the participants' place of employment for HIV and TB diagnostic laboratory programs. It also serves as a follow-on to a previously published manuscript that measured training effectiveness for all courses offered at ACILT.

Methods: ACILT offered 20 Laboratory Biosafety and Infrastructure courses (2008-2014), also referred as biosafety course/course comprising of 14 core laboratory safety elements to 402 participants from 22 countries. In 2015, participants received 22 e-questions divided into four categories: (1) Safety Policies, (2) Management's Engagement, (3) Safety Programs and (4) Assessments of Safety Practices to determine retrospectively the training effectiveness of biosafety practices in their place of employment 6 months before and after attending their course. We used Kirkpatrick model to assess the transference of knowledge, skills and obstructive factors.

Results: 20% (81/402) of the participants completed the e-questionnaire. The overall percentage of positive responses indicating implementation of new safety practices increased from 50% to 84%. Improvement occurred in all four categories after attending the course, with the greatest increases in Safety Policies (67-94%) and Safety Programs (43-91%). Creating a safety committee, allocating resources, and establishing a facility safety policy were important drivers for implementing and maintaining laboratory safety practices. In addition, accredited laboratories and countries with national safety regulations or policies had a higher percentage of improvements. The most reported challenges were inadequate funding and lack of management enforcement.

Conclusions: PEPFAR and other partners' investments in training institutions, such as ACILT, were effective in building sustainable country ownership to strengthen biosafety practices and were leveraged to combat zoonotic diseases and COVID-19. Although support continues at the national/regional level, a standardized, coordinated and continent-wide sustainable approach to offer a biosafety program-like ACILT is missing. Continuous offerings of biosafety programs similar to ACILT could contribute to sustainable strengthening of laboratory biosafety, QMS and pandemic preparedness.

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来源期刊
Tropical Medicine and Health
Tropical Medicine and Health TROPICAL MEDICINE-
CiteScore
7.00
自引率
2.20%
发文量
90
审稿时长
11 weeks
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