{"title":"基于基因组学的药物发现和开发工具:从网络地图到疗效预测","authors":"Junhao Fang , Qi Chen , Guoyu Wu","doi":"10.1016/j.jhip.2023.11.001","DOIUrl":null,"url":null,"abstract":"<div><p>Computing technology plays a crucial role in the field of drug discovery and development. With the rapid development of genomics and the improvement of databases, the application of genomics-based tools is important in drug discovery and development. These tools can deeply explore the information in gene expression profile databases, revealing the connections and interactions between drugs, diseases and genes, and providing strong support for drug discovery and development. This paper introduces various significant genomics-based tools for drug discovery and development, discusses the advantages of deep learning and artificial intelligence in utilizing large-scale genomic data, and reveals the development trends and future prospects of drug genomics tools. The continuous progress of these tools will provide more accurate and efficient support for drug discovery and development.</p></div>","PeriodicalId":100787,"journal":{"name":"Journal of Holistic Integrative Pharmacy","volume":"4 3","pages":"Pages 199-209"},"PeriodicalIF":0.0000,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2707368823001061/pdfft?md5=2fc78205240f5611dd640ec201df07aa&pid=1-s2.0-S2707368823001061-main.pdf","citationCount":"0","resultStr":"{\"title\":\"Genomics-based tools for drug discovery and development: From network maps to efficacy prediction\",\"authors\":\"Junhao Fang , Qi Chen , Guoyu Wu\",\"doi\":\"10.1016/j.jhip.2023.11.001\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Computing technology plays a crucial role in the field of drug discovery and development. With the rapid development of genomics and the improvement of databases, the application of genomics-based tools is important in drug discovery and development. These tools can deeply explore the information in gene expression profile databases, revealing the connections and interactions between drugs, diseases and genes, and providing strong support for drug discovery and development. This paper introduces various significant genomics-based tools for drug discovery and development, discusses the advantages of deep learning and artificial intelligence in utilizing large-scale genomic data, and reveals the development trends and future prospects of drug genomics tools. The continuous progress of these tools will provide more accurate and efficient support for drug discovery and development.</p></div>\",\"PeriodicalId\":100787,\"journal\":{\"name\":\"Journal of Holistic Integrative Pharmacy\",\"volume\":\"4 3\",\"pages\":\"Pages 199-209\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-11-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.sciencedirect.com/science/article/pii/S2707368823001061/pdfft?md5=2fc78205240f5611dd640ec201df07aa&pid=1-s2.0-S2707368823001061-main.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Holistic Integrative Pharmacy\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2707368823001061\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Holistic Integrative Pharmacy","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2707368823001061","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Genomics-based tools for drug discovery and development: From network maps to efficacy prediction
Computing technology plays a crucial role in the field of drug discovery and development. With the rapid development of genomics and the improvement of databases, the application of genomics-based tools is important in drug discovery and development. These tools can deeply explore the information in gene expression profile databases, revealing the connections and interactions between drugs, diseases and genes, and providing strong support for drug discovery and development. This paper introduces various significant genomics-based tools for drug discovery and development, discusses the advantages of deep learning and artificial intelligence in utilizing large-scale genomic data, and reveals the development trends and future prospects of drug genomics tools. The continuous progress of these tools will provide more accurate and efficient support for drug discovery and development.