苯二氮卓类镇痛量表预期值的初步验证。

IF 2.4 3区 医学 Q3 PHARMACOLOGY & PHARMACY Experimental and clinical psychopharmacology Pub Date : 2024-06-01 Epub Date: 2023-11-27 DOI:10.1037/pha0000692
Emma C Lape, Jessica M Powers, Lisa R LaRowe, Joseph W Ditre
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引用次数: 0

摘要

慢性疼痛人群使用苯二氮卓类药物(BZD)的比例更高(与一般人群相比),不按规定使用BZD的可能性更大,并且出现依赖症状。个人报告服用BZD缓解疼痛,可能会导致BZD使用的维持/升级和处方阿片类药物的危险过程。识别疼痛-BZD使用关系的认知因素是理解疼痛在BZD使用轨迹中的作用的关键一步。物质相关镇痛的预期结果与疼痛-物质使用合并症(如酒精)有关,有理由相信这些过程可能延伸到BZD的使用。本研究旨在检验新修订的苯二氮卓类镇痛期望(EBA)量表的心理测量特性,并探讨EBA评分与处方阿片类药物使用行为之间的关系。参与者是306名成年人(38.9%为女性),他们完成了一项在线调查,支持慢性疼痛和目前的BZD处方。结果为EBA的心理测量效度提供了初步的支持:单因素结构的证据具有良好的模型拟合(Bollen-Stine bootstrap p = .101),良好的内部一致性(α = .93),并通过与疼痛变量、不按规定使用BZD的可能性、BZD依赖症状和自我报告使用BZD缓解疼痛的相关性来证明并发效度。在处方阿片类药物的参与者中,探索性发现表明,EBA评分与高风险阿片类药物使用相关行为之间存在正相关变异。据我们所知,这是第一个评估BZD使用镇痛预期的研究。BZD镇痛预期值得进一步研究,作为合并症疼痛和BZD使用的治疗目标。(PsycInfo数据库记录(c) 2023 APA,版权所有)。
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Initial validation of the expectancies for Benzodiazepine Analgesia Scale.

Chronic pain populations exhibit greater prevalence of benzodiazepine (BZD) prescription (vs. the general population) and greater likelihood of BZD use not as prescribed and dependence symptoms. Individuals report taking BZDs for pain relief, potentially contributing to maintenance/escalation of BZD use and hazardous couse with prescription opioids. Identifying cognitive factors underlying pain-BZD use relations represents a critical step toward understanding the role of pain in BZD use trajectories. Outcome expectancies for substance-related analgesia have been implicated in pain-substance use comorbidity (e.g., alcohol), and there is reason to believe these processes may extend to BZD use. The present study aimed to examine psychometric properties of a newly adapted Expectancies for Benzodiazepine Analgesia (EBA) scale and probe associations between EBA scores and prescription opioid use behaviors. Participants were 306 adults (38.9% females) endorsing chronic pain and current BZD prescription who completed an online survey. Results provided initial support for psychometric validity of the EBA: evidence of single-factor structure with good model fit (Bollen-Stine bootstrap p = .101), excellent internal consistency (α = .93), and evidence of concurrent validity via correlations with pain variables, likelihood of BZD use not as prescribed, BZD dependence symptoms, and self-reported BZD use for pain relief. Exploratory findings among participants prescribed opioids indicated positive covariation between EBA scores and behaviors associated with higher risk opioid use. This is, to our knowledge, the first study to assess analgesia expectancies for BZD use. BZD analgesic expectancies warrant further study as a treatment target in comorbid pain and BZD use. (PsycInfo Database Record (c) 2024 APA, all rights reserved).

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来源期刊
CiteScore
4.20
自引率
8.70%
发文量
164
审稿时长
6-12 weeks
期刊介绍: Experimental and Clinical Psychopharmacology publishes advances in translational and interdisciplinary research on psychopharmacology, broadly defined, and/or substance abuse.
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