高颈脊髓损伤患者鞘内巴氯芬泵伴假丝酵母旁裂症的存在感染还是殖民?一个病例报告。

IF 0.7 Q4 CLINICAL NEUROLOGY Spinal Cord Series and Cases Pub Date : 2023-11-30 DOI:10.1038/s41394-023-00610-5
John Chan, Harminder Singh, Kazuko Shem
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引用次数: 0

摘要

鞘内巴氯芬(ITB)治疗是治疗脊髓损伤(SCI)痉挛患者痉挛的有效方法,但并发症并不罕见,包括脊髓液泄漏、感染和导管/泵故障。病例介绍:本研究报告了一名患有创伤性脊髓损伤的成年男性患者的相关信息,该患者既往有两次ITB泵袋感染病史,由于泵感染需要切除。然后,患者在第三个泵处出现皮肤糜烂,泵周围的液体生长出对甲氧西林敏感的金黄色葡萄球菌、类白喉和假丝酵母菌。患者最初接受抗生素和抗真菌药物治疗,未拆除ITB泵。27个月后,ITB泵最终被移除,10个月后,第四个泵被植入。讨论:颅脑泵可作为脊髓损伤患者痉挛的有效治疗方式;然而,可能会发生并发症,包括感染,并需要移除泵。本病例说明了一个可能的念珠菌定植ITB泵的病例,最终被移除。
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The presence of Candida parapsilosis with intrathecal baclofen pump in a person with high cervical spinal cord injury; infection or colonization? A Case Report.

Introduction: Intrathecal baclofen (ITB) therapy is an effective method of treating spasticity in persons with spasticity due to spinal cord injury (SCI), but complications are not rare and can include spinal fluid leaks, infection, and catheter/pump malfunction.

Case presentation: This study presents information related to an adult male patient with traumatic SCI and a history of two prior ITB pump pocket infections that required removal due to pump infection. The patient then developed skin erosion over the third pump, and the fluid around the pump grew methicillin-sensitive Staphylococcus aureus, diphtheroids, and Candida parapsilosis. The patient was initially treated with antibiotics and anti-fungal medication without removal of the ITB pump. The ITB pump was eventually removed 27 months later, and the fourth pump was implanted 10 months later.

Discussion: ITB pumps can be an effective treatment modality for spasticity in people with SCI; however, complications, including infection, can occur and require pump removal. This case illustrates a case of possible Candida colonization of the ITB pump, which was eventually removed.

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来源期刊
Spinal Cord Series and Cases
Spinal Cord Series and Cases Medicine-Neurology (clinical)
CiteScore
2.20
自引率
8.30%
发文量
92
期刊最新文献
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