Gary J. Vogel , William C. Kayser , Michael C. Savides , Matt Edmonds , Nick Van Engen , Tracye M. Edwards , Janet B. Allen , Phillip J. Rincker , Ty E. Lawrence , Floyd K. McKeith , Scott E. Roland , G. Allen Bridges , K.D. Miller , Cory T. Herr
{"title":"去除润滑油对肉牛组织浓度、计算的氨气排放、活产性能和胴体特性的影响","authors":"Gary J. Vogel , William C. Kayser , Michael C. Savides , Matt Edmonds , Nick Van Engen , Tracye M. Edwards , Janet B. Allen , Phillip J. Rincker , Ty E. Lawrence , Floyd K. McKeith , Scott E. Roland , G. Allen Bridges , K.D. Miller , Cory T. Herr","doi":"10.15232/aas.2023-02442","DOIUrl":null,"url":null,"abstract":"<div><h3>Objective</h3><p>Our objective was to evaluate tissue residue levels, calculated NH<sub>3</sub> gas emissions and live and carcass growth in finishing beef steers fed lubabegron (LB).</p></div><div><h3>Materials and Methods</h3><p>In Exp 1, 50 steers were fed ad libitum a diet containing LB at 1.54 or 5.53 mg/kg of DM for 14 d, followed by a voluntary removal duration of 0, 1, 2, 4, 6, or 8 d before slaughter. Nongastrointestinal tract (GI) tissues collected and analyzed were muscle, liver, tongue, heart, bone, bone marrow, and tendon. In Exp 2, 700 steers were supplemented with either a diet containing LB at 3.5 mg/kg of DM or a negative control for 56 d. Supplementation was followed by removal durations of 0, 2, 4, 6, 8, and 16 d before slaughter. At slaughter, a subset of steers (35; 5 per treatment) were selected to sample GI and non-GI tissues for LB residues, and the remaining animals were used to evaluate the live and carcass growth.</p></div><div><h3>Results and Discussion</h3><p>In Exp 1, all non-GI tract tissues were below the 3 μg/kg limit of quantification (LOQ), except for the tongue. At the greater supplementation level (5.53 mg/kg) tongue had residues of 3.80 and 2.08 μg/kg for removal durations 0 and 1 d, respectively. Within GI tissues, steers supplemented with the lower dose (1.54 mg/kg) had detectable residues within the reticulum (0–2 d), rumen (0–1 d), omasum (0–4 d), and abomasum (0–2 d). Steers supplemented with the higher dose (5.53 mg/kg), had detectable residues within the reticulum (0–4 d), rumen (0–2 d), omasum (0–6 d), small intestine (0–1d), and large intestine (0 d). In Exp 2, the LOQ for LB residues was 1 μg/kg, and residues were detectable in liver (0 d), muscle (0–2 d), rumen (0–4 d), reticulum (0–4 d), and omasum (0–16 d). Steers supplemented with LB had greater final BW (<em>P</em> < 0.001), ADG (<em>P</em> < 0.001), G:F (<em>P</em>< 0.001), hot carcass weight (<em>P</em> < 0.001), DP (<em>P</em> < 0.001), and rib-eye area (<em>P</em> < 0.001) than the negative control. Furthermore, steers fed LB exhibited reduced marbling score (<em>P</em> < 0.001) and YG (<em>P</em> < 0.001) compared with control steers. Calculated NH<sub>3</sub> gas emissions were greater (<em>P</em>< 0.001) for control steers (6,204 g/head) compared with LB-supplemented steers (5,202 to 5,348 g/head).</p></div><div><h3>Conclusions and Application</h3><p>These results demonstrate that LB residue concentrations are affected by supplementation concentrations, tissue type, and duration of removal before slaughter. Furthermore, the LB supplementation results in greater red meat yield and decreased calculated NH<sub>3</sub> gas emissions.</p></div>","PeriodicalId":8519,"journal":{"name":"Applied Animal Science","volume":"39 6","pages":"Pages 484-493"},"PeriodicalIF":1.4000,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2590286523000733/pdf?md5=184049bab5f49536e1f38350799fb59f&pid=1-s2.0-S2590286523000733-main.pdf","citationCount":"0","resultStr":"{\"title\":\"Effects of lubabegron removal on tissue concentration, calculated ammonia gas emissions, live performance, and carcass characteristics of beef steers\",\"authors\":\"Gary J. Vogel , William C. Kayser , Michael C. Savides , Matt Edmonds , Nick Van Engen , Tracye M. Edwards , Janet B. Allen , Phillip J. Rincker , Ty E. Lawrence , Floyd K. McKeith , Scott E. Roland , G. Allen Bridges , K.D. Miller , Cory T. Herr\",\"doi\":\"10.15232/aas.2023-02442\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Objective</h3><p>Our objective was to evaluate tissue residue levels, calculated NH<sub>3</sub> gas emissions and live and carcass growth in finishing beef steers fed lubabegron (LB).</p></div><div><h3>Materials and Methods</h3><p>In Exp 1, 50 steers were fed ad libitum a diet containing LB at 1.54 or 5.53 mg/kg of DM for 14 d, followed by a voluntary removal duration of 0, 1, 2, 4, 6, or 8 d before slaughter. Nongastrointestinal tract (GI) tissues collected and analyzed were muscle, liver, tongue, heart, bone, bone marrow, and tendon. In Exp 2, 700 steers were supplemented with either a diet containing LB at 3.5 mg/kg of DM or a negative control for 56 d. Supplementation was followed by removal durations of 0, 2, 4, 6, 8, and 16 d before slaughter. At slaughter, a subset of steers (35; 5 per treatment) were selected to sample GI and non-GI tissues for LB residues, and the remaining animals were used to evaluate the live and carcass growth.</p></div><div><h3>Results and Discussion</h3><p>In Exp 1, all non-GI tract tissues were below the 3 μg/kg limit of quantification (LOQ), except for the tongue. At the greater supplementation level (5.53 mg/kg) tongue had residues of 3.80 and 2.08 μg/kg for removal durations 0 and 1 d, respectively. Within GI tissues, steers supplemented with the lower dose (1.54 mg/kg) had detectable residues within the reticulum (0–2 d), rumen (0–1 d), omasum (0–4 d), and abomasum (0–2 d). Steers supplemented with the higher dose (5.53 mg/kg), had detectable residues within the reticulum (0–4 d), rumen (0–2 d), omasum (0–6 d), small intestine (0–1d), and large intestine (0 d). In Exp 2, the LOQ for LB residues was 1 μg/kg, and residues were detectable in liver (0 d), muscle (0–2 d), rumen (0–4 d), reticulum (0–4 d), and omasum (0–16 d). Steers supplemented with LB had greater final BW (<em>P</em> < 0.001), ADG (<em>P</em> < 0.001), G:F (<em>P</em>< 0.001), hot carcass weight (<em>P</em> < 0.001), DP (<em>P</em> < 0.001), and rib-eye area (<em>P</em> < 0.001) than the negative control. Furthermore, steers fed LB exhibited reduced marbling score (<em>P</em> < 0.001) and YG (<em>P</em> < 0.001) compared with control steers. Calculated NH<sub>3</sub> gas emissions were greater (<em>P</em>< 0.001) for control steers (6,204 g/head) compared with LB-supplemented steers (5,202 to 5,348 g/head).</p></div><div><h3>Conclusions and Application</h3><p>These results demonstrate that LB residue concentrations are affected by supplementation concentrations, tissue type, and duration of removal before slaughter. Furthermore, the LB supplementation results in greater red meat yield and decreased calculated NH<sub>3</sub> gas emissions.</p></div>\",\"PeriodicalId\":8519,\"journal\":{\"name\":\"Applied Animal Science\",\"volume\":\"39 6\",\"pages\":\"Pages 484-493\"},\"PeriodicalIF\":1.4000,\"publicationDate\":\"2023-12-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.sciencedirect.com/science/article/pii/S2590286523000733/pdf?md5=184049bab5f49536e1f38350799fb59f&pid=1-s2.0-S2590286523000733-main.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Applied Animal Science\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2590286523000733\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"AGRICULTURE, DAIRY & ANIMAL SCIENCE\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Applied Animal Science","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2590286523000733","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"AGRICULTURE, DAIRY & ANIMAL SCIENCE","Score":null,"Total":0}
Effects of lubabegron removal on tissue concentration, calculated ammonia gas emissions, live performance, and carcass characteristics of beef steers
Objective
Our objective was to evaluate tissue residue levels, calculated NH3 gas emissions and live and carcass growth in finishing beef steers fed lubabegron (LB).
Materials and Methods
In Exp 1, 50 steers were fed ad libitum a diet containing LB at 1.54 or 5.53 mg/kg of DM for 14 d, followed by a voluntary removal duration of 0, 1, 2, 4, 6, or 8 d before slaughter. Nongastrointestinal tract (GI) tissues collected and analyzed were muscle, liver, tongue, heart, bone, bone marrow, and tendon. In Exp 2, 700 steers were supplemented with either a diet containing LB at 3.5 mg/kg of DM or a negative control for 56 d. Supplementation was followed by removal durations of 0, 2, 4, 6, 8, and 16 d before slaughter. At slaughter, a subset of steers (35; 5 per treatment) were selected to sample GI and non-GI tissues for LB residues, and the remaining animals were used to evaluate the live and carcass growth.
Results and Discussion
In Exp 1, all non-GI tract tissues were below the 3 μg/kg limit of quantification (LOQ), except for the tongue. At the greater supplementation level (5.53 mg/kg) tongue had residues of 3.80 and 2.08 μg/kg for removal durations 0 and 1 d, respectively. Within GI tissues, steers supplemented with the lower dose (1.54 mg/kg) had detectable residues within the reticulum (0–2 d), rumen (0–1 d), omasum (0–4 d), and abomasum (0–2 d). Steers supplemented with the higher dose (5.53 mg/kg), had detectable residues within the reticulum (0–4 d), rumen (0–2 d), omasum (0–6 d), small intestine (0–1d), and large intestine (0 d). In Exp 2, the LOQ for LB residues was 1 μg/kg, and residues were detectable in liver (0 d), muscle (0–2 d), rumen (0–4 d), reticulum (0–4 d), and omasum (0–16 d). Steers supplemented with LB had greater final BW (P < 0.001), ADG (P < 0.001), G:F (P< 0.001), hot carcass weight (P < 0.001), DP (P < 0.001), and rib-eye area (P < 0.001) than the negative control. Furthermore, steers fed LB exhibited reduced marbling score (P < 0.001) and YG (P < 0.001) compared with control steers. Calculated NH3 gas emissions were greater (P< 0.001) for control steers (6,204 g/head) compared with LB-supplemented steers (5,202 to 5,348 g/head).
Conclusions and Application
These results demonstrate that LB residue concentrations are affected by supplementation concentrations, tissue type, and duration of removal before slaughter. Furthermore, the LB supplementation results in greater red meat yield and decreased calculated NH3 gas emissions.