潜在的SARS-CoV-2非结构蛋白15抑制剂:重新利用fda批准的药物

Journal of exploratory research in pharmacology Pub Date : 2021-10-14 DOI:10.14218/jerp.2021.00032

Jason Y Tang,Igor F. Tsigelny,Jerry P. Greenberg,Mark A. Miller,Valentina L. Kouznetsova

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引用次数: 0

摘要

严重急性呼吸综合征冠状病毒(SARS-CoV) 2感染已在全球造成数百万人死亡，迫切需要有效的治疗方法。非结构蛋白15 (NSP15)在SARS-CoV-2逃避宿主先天免疫应答中发挥重要作用，是一个有希望的靶标。

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Potential SARS-CoV-2 Nonstructural Protein 15 Inhibitors: Repurposing FDA-Approved Drugs

Severe acute respiratory syndrome coronavirus (SARS-CoV) 2 infection has caused millions of deaths worldwide, pushing the urgent need for an efficient treatment. Nonstructural protein 15 (NSP15) is a promising target due to its importance for SARS-CoV-2’s evasion of the host’s innate immune response.

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Journal of exploratory research in pharmacology

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