Maia H. Hauschild , Peyton V. Warp , Hansel E. Tookes , Ella Yakir , Bharat Malhotra , Subul Malik , Cyrus Owens , Edward Suarez Jr , David P. Serota , Tyler S. Bartholomew
{"title":"在注射器服务计划诊所就医的注射吸毒者中，异丙嗪的流行率：佛罗里达州迈阿密，2023 年","authors":"Maia H. Hauschild , Peyton V. Warp , Hansel E. Tookes , Ella Yakir , Bharat Malhotra , Subul Malik , Cyrus Owens , Edward Suarez Jr , David P. Serota , Tyler S. Bartholomew","doi":"10.1016/j.dadr.2023.100209","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><p>We aimed to report the preliminary xylazine prevalence among people who inject drugs (PWID) treated at a student-run free clinic in Miami, FL, USA and to identify characteristics associated with screening positive for xylazine.</p></div><div><h3>Methods</h3><p>A retrospective chart review of 59 patients presenting to a syringe services program (SSP) clinic in was conducted between April 27th and August 17th, 2023. We measured presence of xylazine with rapid visual immunoassay strips on patient urine samples.</p></div><div><h3>Results</h3><p>Xylazine was present in 55.9 % (33/59) of urine samples including 2 without detected opioids. Xylazine presence was significantly associated with unsheltered homelessness (<em>p</em> = 0.018), presence of wound(s) (<em>p</em> = 0.008), and testing positive for hepatitis C antibody (<em>p</em> = 0.014), fentanyl (<em>p</em> = 0.005) and MDMA (<em>p</em> = 0.002).</p></div><div><h3>Conclusions</h3><p>A high prevalence of xylazine in the Southeastern United States furthers evidence of the geographical spread of xylazine and rapidly evolving illicit drug supply. Widespread xylazine screening is urgently needed to inform people who inject drugs and to studyinterventions to minimize harms associated with xylazine.</p></div>","PeriodicalId":72841,"journal":{"name":"Drug and alcohol dependence reports","volume":"9 ","pages":"Article 100209"},"PeriodicalIF":0.0000,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772724623000793/pdfft?md5=66c81de8d4f8db3b2681b556aff91f5c&pid=1-s2.0-S2772724623000793-main.pdf","citationCount":"0","resultStr":"{\"title\":\"Prevalence of xylazine among people who inject drugs seeking medical care at a syringe services program clinic: Miami, Florida, 2023\",\"authors\":\"Maia H. Hauschild , Peyton V. Warp , Hansel E. Tookes , Ella Yakir , Bharat Malhotra , Subul Malik , Cyrus Owens , Edward Suarez Jr , David P. Serota , Tyler S. Bartholomew\",\"doi\":\"10.1016/j.dadr.2023.100209\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Background</h3><p>We aimed to report the preliminary xylazine prevalence among people who inject drugs (PWID) treated at a student-run free clinic in Miami, FL, USA and to identify characteristics associated with screening positive for xylazine.</p></div><div><h3>Methods</h3><p>A retrospective chart review of 59 patients presenting to a syringe services program (SSP) clinic in was conducted between April 27th and August 17th, 2023. We measured presence of xylazine with rapid visual immunoassay strips on patient urine samples.</p></div><div><h3>Results</h3><p>Xylazine was present in 55.9 % (33/59) of urine samples including 2 without detected opioids. Xylazine presence was significantly associated with unsheltered homelessness (<em>p</em> = 0.018), presence of wound(s) (<em>p</em> = 0.008), and testing positive for hepatitis C antibody (<em>p</em> = 0.014), fentanyl (<em>p</em> = 0.005) and MDMA (<em>p</em> = 0.002).</p></div><div><h3>Conclusions</h3><p>A high prevalence of xylazine in the Southeastern United States furthers evidence of the geographical spread of xylazine and rapidly evolving illicit drug supply. Widespread xylazine screening is urgently needed to inform people who inject drugs and to studyinterventions to minimize harms associated with xylazine.</p></div>\",\"PeriodicalId\":72841,\"journal\":{\"name\":\"Drug and alcohol dependence reports\",\"volume\":\"9 \",\"pages\":\"Article 100209\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-12-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.sciencedirect.com/science/article/pii/S2772724623000793/pdfft?md5=66c81de8d4f8db3b2681b556aff91f5c&pid=1-s2.0-S2772724623000793-main.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Drug and alcohol dependence reports\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2772724623000793\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Drug and alcohol dependence reports","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2772724623000793","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Prevalence of xylazine among people who inject drugs seeking medical care at a syringe services program clinic: Miami, Florida, 2023
Background
We aimed to report the preliminary xylazine prevalence among people who inject drugs (PWID) treated at a student-run free clinic in Miami, FL, USA and to identify characteristics associated with screening positive for xylazine.
Methods
A retrospective chart review of 59 patients presenting to a syringe services program (SSP) clinic in was conducted between April 27th and August 17th, 2023. We measured presence of xylazine with rapid visual immunoassay strips on patient urine samples.
Results
Xylazine was present in 55.9 % (33/59) of urine samples including 2 without detected opioids. Xylazine presence was significantly associated with unsheltered homelessness (p = 0.018), presence of wound(s) (p = 0.008), and testing positive for hepatitis C antibody (p = 0.014), fentanyl (p = 0.005) and MDMA (p = 0.002).
Conclusions
A high prevalence of xylazine in the Southeastern United States furthers evidence of the geographical spread of xylazine and rapidly evolving illicit drug supply. Widespread xylazine screening is urgently needed to inform people who inject drugs and to studyinterventions to minimize harms associated with xylazine.
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