Drug and alcohol dependence reports最新文献

The psychostimulant drug, fenethylline (captagon): Health risks, addiction and the global impact of illicit trade

Drug and alcohol dependence reports

Pub Date : 2025-03-01 DOI: 10.1016/j.dadr.2025.100323

Matthew Chidozie Ogwu , Matěj Malík , Pavel Tlustoš , Jiří Patočka

Fenethylline (street name, captagon) is a synthetic amphetamine-type stimulant that is emerging as a significant public health and security concern, particularly in the Middle East. This systematic review synthesizes original research articles, epidemiological studies, systematic reviews, policy analyses, and case reports to provide a comprehensive analysis of fenethylline’s health impacts, addiction potential, and dynamics of illicit trade. Initially developed for therapeutic use, fenethylline illicit production and use have escalated, raising concern about its physiological, psychological, and socio-economic impacts. This stimulant profoundly affects the central nervous system, enhancing wakefulness, concentration, and physical stamina while inducing euphoria. These effects come at the cost of serious adverse health outcomes, particularly with prolonged or heavy use, including cardiovascular complications, neurological damage, and addiction. The dependence-forming nature of captagon contributes to escalating substance use disorders, impacting healthcare systems. Beyond its biomedical implications, fenethylline trafficking has become a global issue, with supply chains deeply intertwined with politically unstable regions where illicit economies thrive. The geopolitical dimensions of captagon’s trade amplify its global security threat, influencing international relations and regional stability. This paper underscores the urgent need for systematic data collection and coordinated efforts to regulate illicit fenethylline production and distribution. Strategies such as improved surveillance, public health interventions, and international cooperation are essential to mitigate its escalating risks. Addressing this issue requires a multidisciplinary approach, integrating public health, law enforcement, and policy development to curb its impact on global health and security.

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引用次数: 0

Corrigendum to “Receipt of medication for opioid use disorder among rural and urban veterans health administration patients” [Drug Alcohol Depend. Rep. 14 (2025) 100311]

Drug and alcohol dependence reports

Pub Date : 2025-03-01 DOI: 10.1016/j.dadr.2025.100319

Olivia C. Reynolds , Kathleen F. Carlson , Adam J. Gordon , Robert L. Handley , Benjamin J. Morasco , Todd P. Korthuis , Travis I. Lovejoy , Jessica J. Wyse

引用次数: 0

Protocol for a new family history of addiction density score to aid in the treatment of alcohol and substance use disorders

Drug and alcohol dependence reports

Pub Date : 2025-02-20 DOI: 10.1016/j.dadr.2025.100321

Jessica L. Bourdon , Jordan Wright , Sabrina Verdecanna , Mer W. Francis , Vivia V. McCutcheon

Background

While molecular and non-molecular genetic testing are the gold standard for assessing a person’s familial liability for substance use disorders, such testing is often inaccessible. Family history information collected at intake is an alternative, but tools to effectively utilize this information are excessively complex. The aims of the study are threefold: 1) Describe a protocol for the collection of family history in a thorough and straightforward manner. 2) Provide an algorithm to convert family history information to numerical scores. 3) Present the aggregated results from the pilot testing of the protocol.

Methods

All patients (N = 871) underwent a comprehensive assessment that included the family history protocol. Descriptive statistics, t-tests and Pearson Correlation were used to analyze the scores and determine key differences by demographic categories (sex/race/ethnicity/substance/age).

Results

The protocol asked patients four key questions about 1st and 2nd degree relatives while completing a family pedigree. Answers were transferred into an algorithm to output a score for each patient. This score took affectedness and relatedness of each family member into account. The average number of affected relatives was 5.24 (SD=3.17), and there were significant sex, race, and primary substance score differences.

Conclusions

This study provides the addiction field with a novel, freely available, and easily implementable family history protocol that has several potential clinical applications. While more research is needed, pilot results provide a valuable research tool, insight into a typical family history for those at an inpatient addiction treatment center, and steps toward closing the research-to-practice gap in this field.

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引用次数: 0

Refer2Quit: A pilot referral approach to promote treatment for parents who smoke tobacco through pediatric primary care

Drug and alcohol dependence reports

Pub Date : 2025-02-19 DOI: 10.1016/j.dadr.2025.100322

Brian P. Jenssen , Ngwi Tayong , Hannah Martin , Janani Ramachandran , Shannon Kelleher , Jeritt G. Thayer , Robert W. Grundmeier , Alexander G. Fiks , Robert A. Schnoll

Objective

Evidence-based tobacco treatments are rarely provided to household members who smoke but do not attend a child’s pediatric visit. This pilot study evaluated an electronic health record (EHR)-linked intervention leveraging pediatric visits to identify and engage household members who smoke tobacco in treatment remotely.

Methods

We conducted a single-arm prospective study with household members who smoke at a high-volume pediatric primary care practice. During preventive visits, the EHR system screened parents for tobacco use, automated treatment connections, and prompted referrals for household members who smoke. Referred household members were contacted, consented, and offered nicotine replacement therapy (NRT), quitline counseling, and/or SmokefreeTXT. Outcomes included feasibility (referral rate), effectiveness (treatment acceptance), and acceptability (satisfaction). A 1-month follow-up survey assessed treatment use and smoking cessation (7-day abstinence from combustible tobacco).

Results

Between April 2022 and August 2024, 3478 pediatric patients had additional household members who smoke. Of 352 (10.1 %) referred individuals, 350 were contacted; 91 (25.9 %) accepted treatment. Among these, 82 (90 %) chose NRT, 58 (64 %) chose quitline, and 64 (70 %) chose SmokefreeTXT. All participants found the referral approach acceptable. At follow-up, 54 (59 %) completed the survey; 42 (46 %) reported treatment use, and 12 (13 %) reported smoking cessation.

Conclusions

This EHR-linked intervention effectively identifies and engages household members who use tobacco in treatment, demonstrating feasibility, acceptability, and promising outcomes. These findings warrant more rigorous evaluation.

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引用次数: 0

High-intensity interval training alleviates ethanol-induced renal damage: A study on inflammation, oxidative stress, and histopathological changes in rats

Drug and alcohol dependence reports

Pub Date : 2025-02-06 DOI: 10.1016/j.dadr.2025.100320

Najmeh Sadat Hosseini , Sara Shirazpour , Gholamreza Sepehri , Shahriar Dabiri , Manzumeh Shamsi Meymandi

Background

This study examines if high-intensity interval training (HIIT) can reduce ethanol-induced kidney damage by modulating cytokines and reducing oxidative stress.

Method

Thirty male Wistar rats were randomly assigned to five groups (n = 6): CON (saline control), ET (ethanol; 3 mg/kg of 20 % ethanol gavage), HIIT (8 weeks of HIIT), HIIT-SL (saline + HIIT), and HIIT-ET (ethanol + HIIT). Kidney tissues were collected for biochemical analysis of cytokines, including tumor necrosis factor-alpha (TNF-α), interleukin-6 (IL-6), and interleukin-10 (IL-10); oxidative stress markers, including malondialdehyde (MDA); and antioxidants, including total antioxidant capacity (TAC), glutathione peroxidase (GPx), and superoxide dismutase (SOD). Histopathology and serum levels of albumin, urea, and creatinine were evaluated. Statistical significance was assessed using GraphPad Prism (p < 0.05).

Results

Chronic ethanol consumption increased pro-inflammatory cytokines TNF-α and IL-6 (p < 0.0001) and decreased anti-inflammatory IL-10 (p < 0.0001). Histopathology revealed tubular necrosis, and hyaline casts. HIIT reduced TNF-α and IL-6 while increasing IL-10 (p < 0.0001), showing an anti-inflammatory effect. The HIIT-ET group had fewer hyaline casts and less tubular necrosis compared to the ET group, although hyperemia persisted. HIIT improved antioxidant levels (TAC, GPx, SOD) and reduced oxidative stress (MDA) (p < 0.05). Serum urea and creatinine were higher in the ET group but lower in the HIIT-ET group; albumin levels were increased with HIIT.

Conclusion

The study shows HIIT effectively reduces ET-induced kidney damage by decreasing oxidative stress and inflammation, suggesting it as a promising non-drug approach to manage ET-related renal issues.

{"title":"High-intensity interval training alleviates ethanol-induced renal damage: A study on inflammation, oxidative stress, and histopathological changes in rats","authors":"Najmeh Sadat Hosseini , Sara Shirazpour , Gholamreza Sepehri , Shahriar Dabiri , Manzumeh Shamsi Meymandi","doi":"10.1016/j.dadr.2025.100320","DOIUrl":"10.1016/j.dadr.2025.100320","url":null,"abstract":"<div><h3>Background</h3><div>This study examines if high-intensity interval training (HIIT) can reduce ethanol-induced kidney damage by modulating cytokines and reducing oxidative stress.</div></div><div><h3>Method</h3><div>Thirty male Wistar rats were randomly assigned to five groups (n = 6): CON (saline control), ET (ethanol; 3mg/kg of 20 % ethanol gavage), HIIT (8 weeks of HIIT), HIIT-SL (saline + HIIT), and HIIT-ET (ethanol + HIIT). Kidney tissues were collected for biochemical analysis of cytokines, including tumor necrosis factor-alpha (TNF-α), interleukin-6 (IL-6), and interleukin-10 (IL-10); oxidative stress markers, including malondialdehyde (MDA); and antioxidants, including total antioxidant capacity (TAC), glutathione peroxidase (GPx), and superoxide dismutase (SOD). Histopathology and serum levels of albumin, urea, and creatinine were evaluated. Statistical significance was assessed using GraphPad Prism (p < 0.05).</div></div><div><h3>Results</h3><div>Chronic ethanol consumption increased pro-inflammatory cytokines TNF-α and IL-6 (p < 0.0001) and decreased anti-inflammatory IL-10 (p < 0.0001). Histopathology revealed tubular necrosis, and hyaline casts. HIIT reduced TNF-α and IL-6 while increasing IL-10 (p < 0.0001), showing an anti-inflammatory effect. The HIIT-ET group had fewer hyaline casts and less tubular necrosis compared to the ET group, although hyperemia persisted. HIIT improved antioxidant levels (TAC, GPx, SOD) and reduced oxidative stress (MDA) (p < 0.05). Serum urea and creatinine were higher in the ET group but lower in the HIIT-ET group; albumin levels were increased with HIIT.</div></div><div><h3>Conclusion</h3><div>The study shows HIIT effectively reduces ET-induced kidney damage by decreasing oxidative stress and inflammation, suggesting it as a promising non-drug approach to manage ET-related renal issues.</div></div>","PeriodicalId":72841,"journal":{"name":"Drug and alcohol dependence reports","volume":"14 ","pages":"Article 100320"},"PeriodicalIF":0.0,"publicationDate":"2025-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143420504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sex differences in normative modeling of cortical thickness in cannabis use disorder

Drug and alcohol dependence reports

Pub Date : 2025-01-10 DOI: 10.1016/j.dadr.2025.100318

Erin L. Martin , Laura M. Campbell , Kathryn Thorn , Gregory L. Sahlem , Aimee L. McRae-Clark , Andreana Benitez

Cannabis use disorder (CUD) is associated with sexually dimorphic behavioral and neurobiological effects, but sex differences in a broader sampling of brain structures in CUD assessed relative to normative reference values have not been examined. Here, we assessed sex differences in brain regions measured via 3 T MRI in 72 adults (50 males, 22 females) with CUD. T1-weighted images, segmented via FreeSurfer, were used to derive Normative Morphometry Imaging Statistics z-scores (accounting for age, sex, intracranial volume, and image quality). Z-scores were then compared between sexes and associated with behavioral data. We found that average z-scores were within normative ranges for both sexes. There were no sex differences in total brain, cerebral white matter, and subcortical gray matter z-scores, but total cortical thickness z-scores were greater in females. Fourteen cortical regions surrounding the central and lateral sulci had greater z-scores in females than in males, but the medial orbitofrontal cortex z-score was greater in males. Of these regions, 3 were positively correlated with cannabis-related problems. Findings suggest sexual dimorphism in brain structure in CUD primarily in the frontal, medial parietal, and superior temporal lobes, with some association with cannabis-related problems even in the context of normative brain structure. Future research is needed to clarify causal mechanisms of morphometric differences in CUD.

{"title":"Sex differences in normative modeling of cortical thickness in cannabis use disorder","authors":"Erin L. Martin , Laura M. Campbell , Kathryn Thorn , Gregory L. Sahlem , Aimee L. McRae-Clark , Andreana Benitez","doi":"10.1016/j.dadr.2025.100318","DOIUrl":"10.1016/j.dadr.2025.100318","url":null,"abstract":"<div><div>Cannabis use disorder (CUD) is associated with sexually dimorphic behavioral and neurobiological effects, but sex differences in a broader sampling of brain structures in CUD assessed relative to normative reference values have not been examined. Here, we assessed sex differences in brain regions measured via 3T MRI in 72 adults (50 males, 22 females) with CUD. T1-weighted images, segmented via FreeSurfer, were used to derive Normative Morphometry Imaging Statistics z-scores (accounting for age, sex, intracranial volume, and image quality). Z-scores were then compared between sexes and associated with behavioral data. We found that average z-scores were within normative ranges for both sexes. There were no sex differences in total brain, cerebral white matter, and subcortical gray matter z-scores, but total cortical thickness z-scores were greater in females. Fourteen cortical regions surrounding the central and lateral sulci had greater z-scores in females than in males, but the medial orbitofrontal cortex z-score was greater in males. Of these regions, 3 were positively correlated with cannabis-related problems. Findings suggest sexual dimorphism in brain structure in CUD primarily in the frontal, medial parietal, and superior temporal lobes, with some association with cannabis-related problems even in the context of normative brain structure. Future research is needed to clarify causal mechanisms of morphometric differences in CUD.</div></div>","PeriodicalId":72841,"journal":{"name":"Drug and alcohol dependence reports","volume":"14 ","pages":"Article 100318"},"PeriodicalIF":0.0,"publicationDate":"2025-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11783377/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143082463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association of safer smoking supply distribution with participant encounters and naloxone distribution from syringe services programs: Findings from the National Survey of Syringe Services Programs in the United States

Drug and alcohol dependence reports

Pub Date : 2024-12-31 DOI: 10.1016/j.dadr.2024.100317

Esther O. Chung , Sheila V. Patel , Lynn D. Wenger , Jamie L. Humphrey , Amang Sukasih , Ricky N. Bluthenthal , Hansel E. Tookes , Don C. Des Jarlais , Sara N. Glick , Paul A. LaKosky , Stephanie Prohaska , Laura Guzman , Alex H. Kral , Barrot H. Lambdin

Background

In response to the recent and growing shift from injecting heroin to smoking fentanyl, an increasing number of syringe services programs (SSPs) in the United States are distributing safer smoking supplies. There is a lack of research on whether safer smoking supply distribution is associated with increased SSP engagement and naloxone distribution from SSPs. Therefore, we aimed to assess predictors of safer smoking supply distribution by SSPs and estimate associations between safer smoking supply distribution and scale of harm reduction services.

Methods

We used cross-sectional data from the National Survey of Syringe Services Programs, which surveyed SSPs from March and August 2023 about services delivered in 2022. We examined factors associated with safer smoking supply distribution and estimated associations between smoking supply distribution and the number of participant encounters and naloxone doses distributed.

Results

Of the 429 SSPs included, 187 (44.1 %) distributed safer smoking supplies to participants. SSP organizational type, service delivery method, urbanicity, and regional Census divisions were associated with safer smoking supply distribution. Compared to SSPs that did not distribute safer smoking supplies, those that did reported more participant encounters (aRR=1.62, 95 % CI: 1.19–2.20) and naloxone doses distributed (aRR=1.26, 95 % CI: 0.91–1.74).

Conclusions

SSPs distributing safer smoking supplies had greater participant engagement and naloxone distribution. To maximize their full individual and population-level health benefits, SSPs should be supported technically, legally, and financially to implement safer smoking supply distribution for their participants.

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引用次数: 0

Predictors for recurrence of drug use among males on probation for methamphetamine use in Japan: a one-year follow-up study

Drug and alcohol dependence reports

Pub Date : 2024-12-27 DOI: 10.1016/j.dadr.2024.100316

Ayumi Takano , Kunihiko Takahashi , Tatsuhiko Anzai , Takashi Usami , Shiori Tsutsumi , Yuka Kanazawa , Yousuke Kumakura , Toshihiko Matsumoto

Background

Methamphetamine use is related to severe health, social, and criminal challenges. However, there is limited evidence regarding the factors associated with the recurrence of drug use among individuals who have used methamphetamine, particularly within populations involved in the criminal justice system. This study aimed to identify predictors of illicit drug use at a one-year follow-up among males in Japan who have used methamphetamine and are involved in the criminal justice system.

Methods

The study participants were adult males on probation due to methamphetamine use or possession and were involved in a community-based program. The participants were recruited early in their probation period and participated in telephone-based surveys conducted by mental health center staff. We analyzed one-year follow-up data to investigate the recurrence rate of illicit drug use and associated risk factors using multiple logistic regression.

Results

Out of 234 participants, 27 (11.5 %) used illicit drugs during the one-year follow-up period. After adjusting for demographic characteristics, severity of drug use, type of probation, and use of treatment for substance use disorders, the use of social welfare services (OR = 2.78) and a lack of trustworthy relationships (OR = 3.17) were significantly associated with recurrence of illicit drug use.

Conclusions

This study suggested that individuals facing challenges in maintaining stable living conditions and building trustworthy relationships were more likely to return to drug use early in their probation period. Comprehensive and tailored support focused on social stabilization and relationship-building is recommended to aid recovery in males who have experienced methamphetamine use.

背景：吸食甲基苯丙胺与严重的健康、社会和犯罪问题有关。然而，关于吸食过甲基苯丙胺的人再次吸毒的相关因素，特别是涉及刑事司法系统的人群，目前证据有限。本研究旨在确定曾吸食过甲基苯丙胺并卷入刑事司法系统的日本男性在一年随访中使用非法药物的预测因素：研究对象是因吸食或持有甲基苯丙胺而被判缓刑并参与社区项目的成年男性。参与者在缓刑期初期被招募，并参加了由心理健康中心工作人员进行的电话调查。我们分析了一年的随访数据，利用多元逻辑回归法调查了非法药物使用的复发率和相关风险因素：在 234 名参与者中，有 27 人（11.5%）在一年的随访期间使用过非法药物。在对人口统计学特征、吸毒严重程度、缓刑类型和药物使用障碍治疗进行调整后，使用社会福利服务（OR = 2.78）和缺乏值得信赖的关系（OR = 3.17）与再次吸毒显著相关：这项研究表明，在维持稳定的生活条件和建立值得信赖的人际关系方面面临挑战的人更有可能在缓刑期初期重新吸毒。建议为曾吸食甲基苯丙胺的男性提供以社会稳定和建立关系为重点的全面和有针对性的支持，以帮助他们康复。

{"title":"Predictors for recurrence of drug use among males on probation for methamphetamine use in Japan: a one-year follow-up study","authors":"Ayumi Takano , Kunihiko Takahashi , Tatsuhiko Anzai , Takashi Usami , Shiori Tsutsumi , Yuka Kanazawa , Yousuke Kumakura , Toshihiko Matsumoto","doi":"10.1016/j.dadr.2024.100316","DOIUrl":"10.1016/j.dadr.2024.100316","url":null,"abstract":"<div><h3>Background</h3><div>Methamphetamine use is related to severe health, social, and criminal challenges. However, there is limited evidence regarding the factors associated with the recurrence of drug use among individuals who have used methamphetamine, particularly within populations involved in the criminal justice system. This study aimed to identify predictors of illicit drug use at a one-year follow-up among males in Japan who have used methamphetamine and are involved in the criminal justice system.</div></div><div><h3>Methods</h3><div>The study participants were adult males on probation due to methamphetamine use or possession and were involved in a community-based program. The participants were recruited early in their probation period and participated in telephone-based surveys conducted by mental health center staff. We analyzed one-year follow-up data to investigate the recurrence rate of illicit drug use and associated risk factors using multiple logistic regression.</div></div><div><h3>Results</h3><div>Out of 234 participants, 27 (11.5 %) used illicit drugs during the one-year follow-up period. After adjusting for demographic characteristics, severity of drug use, type of probation, and use of treatment for substance use disorders, the use of social welfare services (OR = 2.78) and a lack of trustworthy relationships (OR = 3.17) were significantly associated with recurrence of illicit drug use.</div></div><div><h3>Conclusions</h3><div>This study suggested that individuals facing challenges in maintaining stable living conditions and building trustworthy relationships were more likely to return to drug use early in their probation period. Comprehensive and tailored support focused on social stabilization and relationship-building is recommended to aid recovery in males who have experienced methamphetamine use.</div></div>","PeriodicalId":72841,"journal":{"name":"Drug and alcohol dependence reports","volume":"14 ","pages":"Article 100316"},"PeriodicalIF":0.0,"publicationDate":"2024-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11757224/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143048736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A mixed-methods investigation of an ecological momentary assessment protocol for cigarette-smoking youth: Psychometric properties and participant experiences

Drug and alcohol dependence reports

Pub Date : 2024-12-25 DOI: 10.1016/j.dadr.2024.100314

Suhaavi Kochhar , Hanneke Scholten , Dominique F Maciejewski , Michelle A Pingel , Maartje Luijten

Introduction

Ecological momentary assessment (EMA) is popular in smoking research to study time-varying processes and design just-in-time personalised cessation interventions. Yet, research examining the psychometric properties of EMA and user experiences with EMA protocols is lacking. We conducted a mixed-methods study to test the EMA component of a mobile intervention for middle to late-aged adolescents (16–20 years) who smoke cigarettes at least weekly.

Method

Participants (N = 84) filled out global self-report measures at pre- and post-test, and reported their craving, mood, and smoking behaviour five times daily for seven days via their phones. We tested intra-class correlations, convergent validity, test-retest reliability, and multilevel internal consistency of the EMA items. Further, participants answered qualitative questions about their experiences with the EMA including the timing and frequency of assessments, clarity of individual items, and how it impacted their daily lives.

Results

The EMA questionnaires showed good convergent validity and reliability. The average compliance rate was 77 %, and generally, participants evaluated the experience positively. While most participants rated the timing and frequency of EMA positively, some participants did not like that assessments expired after 1.5 h. Forty percent of participants also reported that they liked monitoring their smoking and mood.

Conclusions

The use of EMA in our target group is feasible and had good compliance. The items used are suitable for researchers to use in future studies. We urge researchers to test the psychometric quality and feasibility of new EMA protocols before using them in confirmatory research.

导言：生态瞬间评估（EMA）在吸烟研究中非常流行，用于研究时间变化过程和设计适时的个性化戒烟干预措施。然而，有关 EMA 心理测量特性和用户使用 EMA 协议体验的研究却十分缺乏。我们开展了一项混合方法研究，以测试针对至少每周吸烟的中晚年青少年（16-20 岁）的移动干预中的 EMA 部分：参与者（84 人）在测试前和测试后填写了全面的自我报告，并在七天内每天五次通过手机报告他们的渴望、情绪和吸烟行为。我们测试了 EMA 项目的类内相关性、收敛有效性、重测可靠性和多层次内部一致性。此外，参与者还回答了有关他们使用 EMA 的体验的定性问题，包括评估的时间和频率、单个项目的清晰度以及 EMA 对他们日常生活的影响：EMA 问卷显示出良好的收敛效度和可靠性。平均符合率为 77%，参与者普遍对此次体验给予了积极评价。虽然大多数参与者对 EMA 的时间和频率给予了积极评价，但一些参与者不喜欢评估在 1.5 小时后失效。40%的参与者还表示，他们喜欢监测自己的吸烟情况和情绪：结论：在我们的目标群体中使用 EMA 是可行的，而且依从性良好。所使用的项目适合研究人员在今后的研究中使用。我们敦促研究人员在将新的 EMA 方案用于确证研究之前，对其心理测量质量和可行性进行测试。

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引用次数: 0

Intimate partner sexual violence is associated with unhealthy alcohol use among Kenyan women engaged in sex work

Drug and alcohol dependence reports

Pub Date : 2024-12-25 DOI: 10.1016/j.dadr.2024.100315

Daniel Tolstrup , Sarah T. Roberts , Ruth Deya , George Wanje , Juma Shafi , Jocelyn R. James , Geetanjali Chander , R. Scott McClelland , Susan M. Graham

Aim

Unhealthy alcohol use is often correlated with experiences of intimate partner violence (IPV). We investigated how different types of IPV (sexual, physical, emotional, and financial) were associated with unhealthy alcohol use among women engaged in sex work in Mombasa, Kenya.

Methods

This cross-sectional study included 283 HIV-negative women who engaged in sex work recruited from an ongoing cohort study. Modified Poisson analysis was used to assess associations between recent (≤ 12 months) or past (> 12 months) experiences of sexual, physical, emotional, or financial IPV and unhealthy alcohol use defined as an Alcohol Use Disorders Identification Test score ≥ 8.

Results

Among 283 participants, 34.6 % had unhealthy alcohol use. Physical (62.5 %), emotional (60.4 %), and financial (66.4 %) IPV occurred more frequently than sexual IPV (43.8 %). Adjusted risk ratios (ARR) for relationships between physical and financial IPV and unhealthy alcohol use were elevated but not statistically significant. Compared to participants who had not experienced sexual IPV, those who had experienced recent or past sexual IPV had an increased risk of unhealthy alcohol use (ARR 1.56, 95 % confidence interval [1.09, 2.23] and ARR 1.48, 95 % confidence interval [0.97, 2.25], respectively).

Conclusion

Sexual IPV was associated with unhealthy alcohol use among Kenyan women who engage in sex work. Physical, emotional, and financial IPV were also highly prevalent in the study population, though not associated with unhealthy alcohol use. These findings affirm the potential benefit of providing integrated IPV and alcohol treatment services focused on recovery after experiences of IPV for this vulnerable population.

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引用次数: 0