Asma A. Taha, A. M. Eisen, Hana Q. Abdul Rahman, Kelsey E. Good, Kurt A. Freeman, Jennifer D. Kotzin, Margaret H. Wolf, N. Azar, Kelley R. Davis, J. C. Austin
{"title":"海绵体造口管改善了脊柱裂儿科患者的肠道连续性:对一家诊所成果的回顾性分析","authors":"Asma A. Taha, A. M. Eisen, Hana Q. Abdul Rahman, Kelsey E. Good, Kurt A. Freeman, Jennifer D. Kotzin, Margaret H. Wolf, N. Azar, Kelley R. Davis, J. C. Austin","doi":"10.3233/prm-220123","DOIUrl":null,"url":null,"abstract":"PURPOSE: Pediatric patients with spina bifida often experience neurogenic bowel dysfunction. Although cecostomy tubes could improve bowel continence, their effectiveness is not well established in this population. The aims of this study were to better understand the effectiveness of cecostomy tubes relative to other management strategies (between-subject) and to explore their effectiveness among patients who received these placements (within-subject). METHODS: Retrospective analysis of data from pediatric patients enrolled in a national spina bifida patient registry (n = 297) at a single multidisciplinary clinic was performed, covering visits between January 2014 –December 2021. Linear and ordinal mixed effect models (fixed and random effects) tested the influence of cecostomy status (no placement vs placement) and time (visits) on bowel continence while controlling for demographic and condition-specific covariates. RESULTS: Patients with cecostomy tubes had higher bowel continence compared to patients without placements (B = 0.695, 95% CI [0.333, 1.050]; AOR = 2.043, p = .007). Patients with cecostomy tubes had higher bowel continence after their placements compared to before (B = 0.834, 95% CI [0.142, 1.540]; AOR = 3.259, p = 0.011). CONCLUSION: Results indicate cecostomy tubes are effective for improving bowel continence in this pediatric population. Future research is needed to conduct risk analyses and determine the clinical significance of these effects.","PeriodicalId":16692,"journal":{"name":"Journal of pediatric rehabilitation medicine","volume":"17 6","pages":""},"PeriodicalIF":0.8000,"publicationDate":"2023-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Cecostomy tubes improve bowel continence for pediatric patients with spina bifida: A retrospective analysis of outcomes from a single clinic\",\"authors\":\"Asma A. Taha, A. M. Eisen, Hana Q. Abdul Rahman, Kelsey E. Good, Kurt A. Freeman, Jennifer D. Kotzin, Margaret H. Wolf, N. Azar, Kelley R. Davis, J. C. Austin\",\"doi\":\"10.3233/prm-220123\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"PURPOSE: Pediatric patients with spina bifida often experience neurogenic bowel dysfunction. Although cecostomy tubes could improve bowel continence, their effectiveness is not well established in this population. The aims of this study were to better understand the effectiveness of cecostomy tubes relative to other management strategies (between-subject) and to explore their effectiveness among patients who received these placements (within-subject). METHODS: Retrospective analysis of data from pediatric patients enrolled in a national spina bifida patient registry (n = 297) at a single multidisciplinary clinic was performed, covering visits between January 2014 –December 2021. Linear and ordinal mixed effect models (fixed and random effects) tested the influence of cecostomy status (no placement vs placement) and time (visits) on bowel continence while controlling for demographic and condition-specific covariates. RESULTS: Patients with cecostomy tubes had higher bowel continence compared to patients without placements (B = 0.695, 95% CI [0.333, 1.050]; AOR = 2.043, p = .007). Patients with cecostomy tubes had higher bowel continence after their placements compared to before (B = 0.834, 95% CI [0.142, 1.540]; AOR = 3.259, p = 0.011). CONCLUSION: Results indicate cecostomy tubes are effective for improving bowel continence in this pediatric population. 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引用次数: 0
摘要
目的:小儿脊柱裂患者常经历神经源性肠功能障碍。虽然结肠造口管可以改善肠失禁,但其有效性在这一人群中尚未得到很好的证实。本研究的目的是为了更好地了解相对于其他管理策略(受试者之间)的结肠造口管的有效性,并探讨它们在接受这些放置的患者中的有效性(受试者内)。方法:回顾性分析2014年1月至2021年12月在一家多学科诊所登记的国家脊柱裂患者登记处(n = 297)的儿科患者的数据。线性和有序混合效应模型(固定效应和随机效应)在控制人口统计学和条件特异性协变量的同时,测试了结肠切除状态(无放置vs放置)和时间(就诊)对肠失禁的影响。结果:与未置入结肠造口管的患者相比,置入结肠造口管的患者肠失禁发生率更高(B = 0.695, 95% CI [0.333, 1.050];AOR = 2.043, p = .007)。置入结肠造口管后患者的肠失禁发生率高于置入前(B = 0.834, 95% CI [0.142, 1.540];AOR = 3.259, p = 0.011)。结论:结果表明,结肠造口管是改善儿童肠道失禁的有效方法。未来的研究需要进行风险分析,并确定这些影响的临床意义。
Cecostomy tubes improve bowel continence for pediatric patients with spina bifida: A retrospective analysis of outcomes from a single clinic
PURPOSE: Pediatric patients with spina bifida often experience neurogenic bowel dysfunction. Although cecostomy tubes could improve bowel continence, their effectiveness is not well established in this population. The aims of this study were to better understand the effectiveness of cecostomy tubes relative to other management strategies (between-subject) and to explore their effectiveness among patients who received these placements (within-subject). METHODS: Retrospective analysis of data from pediatric patients enrolled in a national spina bifida patient registry (n = 297) at a single multidisciplinary clinic was performed, covering visits between January 2014 –December 2021. Linear and ordinal mixed effect models (fixed and random effects) tested the influence of cecostomy status (no placement vs placement) and time (visits) on bowel continence while controlling for demographic and condition-specific covariates. RESULTS: Patients with cecostomy tubes had higher bowel continence compared to patients without placements (B = 0.695, 95% CI [0.333, 1.050]; AOR = 2.043, p = .007). Patients with cecostomy tubes had higher bowel continence after their placements compared to before (B = 0.834, 95% CI [0.142, 1.540]; AOR = 3.259, p = 0.011). CONCLUSION: Results indicate cecostomy tubes are effective for improving bowel continence in this pediatric population. Future research is needed to conduct risk analyses and determine the clinical significance of these effects.