镜像神经元功能的临床应用和疗效

Aleksandra Musioł, Hanna Paluch, Anna Samoń-Drzewicka, Anna Marcinkowska-Gapińska
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引用次数: 0

摘要

镜像疗法的目的是利用大脑镜像神经元的功能,模仿健康身体部位的生理活动,恢复身体残疾部位的功能。镜像神经元的存在首先是在猴子的大脑中发现的,然后它们被证明在人脑中也存在。工作模式总是一样的。如果一个肢体动了,大脑中正确的部分就会被激活,负责刺激其他肢体的镜像神经元也会被激活。这就是大脑中“镜子”的工作原理。这种疗法使用一个一面有镜子的盒子,把受损的肢体藏在盒子里。当一个健康的肢体运动时,它会反映在镜子里。大脑接收到的是一个无效肢体的运动,尽管这只是一种错觉。它驱动神经关节的募集,并提供神经通路的重建。镜像神经元的活动被用于康复、镜像治疗(MT)、观察性动作治疗(AOT)及其变体,如基于虚拟现实(VR)的治疗。这种治疗在幻肢痛(PLP)和中风后综合征(如运动失语、下肢或上肢偏瘫)中观察到显著的效果。在一些精神疾病或自闭症患者的情绪学习中,有使用MT的报道。这篇综述概述了目前基于镜像神经元功能的治疗方法的可能性和希望。
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Clinical applications and efficacy of mirror neuron function
Mirror therapy aims to restore the function of a disabled body part by using the function of mirror neurons in the brain and mimicking the physiological activity of a healthy body part.  The existence of mirror neurons was first discovered in the monkey brain, then they were proven to occur in the human brain. The working pattern is always the same. If one limb moves, the correct part of the brain is activated and the mirror neurons responsible for stimulating the other limbs are activated. This is how the "mirror" in the brain works. The therapy uses a box with a mirror on one side and hides the impaired limb in it.. When a healthy limb moves, it is reflected in the mirror. The brain receives it as a movement of an inefficient limb, even though it is only an illusion. It drives the recruitment of neural joints and provides the reconstruction of neural pathways. The activity of mirror neurons is used in rehabilitation, in mirror therapy (MT), observational action therapy (AOT) and their variants, such as therapies based on Virtual Reality (VR). A significant effect of this treatment was observed in phantom limb pain (PLP) and post-stroke syndromes, such as motor aphasia, hemiparesis of the lower or upper limb. There are reports on the use of MT in some mental diseases or in autistic people in learning emotions. This review outlines the current possibilities and hopes for therapies based on mirror neuron functions based on selected cases.
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发文量
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审稿时长
10 weeks
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