胃肠道内热肥胖症患者的猫肠嵌入术效果:随机对照试验

IF 1.9 4区 医学 Q3 INTEGRATIVE & COMPLEMENTARY MEDICINE European Journal of Integrative Medicine Pub Date : 2024-02-01 DOI:10.1016/j.eujim.2023.102327
Qingqing Zhu , Jian Cheng , Xiaolan Xu , Tangying Xu , Xingjiang Gu , Yun Xia , Lingzhen Mao , Nannan Hu , Yuexia Fang
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引用次数: 0

摘要

导言:在全球范围内,肥胖症的发病率越来越高,导致高血压、糖尿病和心血管疾病的发病率增加。穴位埋线是中国流行的一种针灸方法,在控制体重方面比针灸更有效。方法在这项随机对照试验中,60 名胃肠道内热型肥胖患者被随机分为干预组(30 人)和对照组(30 人)。干预组在饮食和运动的基础上进行为期 2 个月的猫肠嵌入治疗,猫肠治疗频率为每 10 天一次,每次 30 分钟。对照组在同一时期只进行饮食和运动。对治疗前后的体重、体重指数(BMI)、腰臀比(WHR)、空腹血浆葡萄糖、2 小时血糖、糖化血红蛋白和血脂水平进行了评估。2 个月后,与对照组相比,干预组的 WHR 和胃肠道内热型临床症状总分均呈显著下降趋势(平均差:-0.03,95% 置信度(P<0.05)):-0.03,95% 置信度 [CI]:平均差:-0.03,95%置信水平[CI]:-0.07 至 0.00,平均差:-6.04,95%置信水平[CI]:-0.00分别为-6.04,95% 置信度[CI]:-8.59 至-3.50)。在干预组中,体重和体重指数的平均降幅分别为 6.18 千克(95% CI:4.60 至 7.76)和 2.23 千克/平方米(95% CI:1.72 至 2.74)。干预组和对照组治疗脂肪肝的总有效率分别为 61.5%和 30.8%(风险比:3.60;95% CI:1.14 至 11.35)。干预组在体重、体重指数、WHR、胃肠道内热型临床症状总分以及代谢功能障碍相关性脂肪肝的治疗效果方面均优于对照组。本研究得到了杭州市医药卫生科技项目和杭州市临安区中医院的支持。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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The effects of catgut embedding in patients with obesity of gastrointestinal internal heat: A randomised controlled trial

Introduction

Globally, the incidence of obesity is increasing, causing increased rates of hypertension, diabetes, and cardiovascular diseases. Acupoint catgut embedding, a popular acupuncture method in China, has greater efficacy than acupuncture for weight control. The effectiveness of catgut embedding in patients with fatty liver associated with metabolic dysfunction was investigated.

Methods

In this randomised controlled trial, 60 patients with gastrointestinal internal heat-type obesity were randomised to the intervention (n = 30) and control (n = 30) groups. The intervention group participated in the catgut embeddings with diet and exercise for 2 months, with a catgut treatment frequency of once every 10 days for 30 min. The control group participated only in diet and exercise for the same period. Body weight; body mass index (BMI); waist-to-hip ratio (WHR); fasting plasma glucose, 2-hour blood glucose, glycated haemoglobin, and lipid levels were assessed before and after treatments.

Results

Fifty-seven patients completed the courses. After 2 months, the intervention group showed a statistically significant trend of decrease in WHR and total score of gastrointestinal internal heat-type clinical symptoms when compared with the control group (mean difference: −0.03, 95 % confidence level [CI]: −0.07 to 0.00 and mean difference: −6.04, 95 % CI: −8.59 to −3.50, respectively). In the intervention group, the mean reductions in body weight and BMI were 6.18 kg (95 % CI: 4.60 to 7.76) and 2.23 kg/m2 (95 % CI: 1.72 to 2.74), respectively. The total treatment efficiency for fatty liver in the intervention and control groups was 61.5 % and 30.8 %, respectively (risk ratio: 3.60; 95 % CI: 1.14 to 11.35).

Conclusion

Catgut embedding administered with diet and exercise is effective for patients with gastrointestinal internal heat-type obesity and some patients with obesity complicated by metabolic dysfunction-associated fatty liver disease. The effects observed in the intervention group were superior to those in the control group in terms of body weight, BMI, WHR, total score of gastrointestinal internal heat-type clinical symptoms, and treatment effectiveness for metabolic dysfunction-associated fatty liver disease. There were no serious adverse reactions during the treatment.

Registration number

ChiCTR2200057237.

Funding

This study was supported by the Hangzhou Medicine and Health Science and Technology Program and Hangzhou Lin'an District Hospital of Traditional Chinese Medicine.

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来源期刊
European Journal of Integrative Medicine
European Journal of Integrative Medicine INTEGRATIVE & COMPLEMENTARY MEDICINE-
CiteScore
4.70
自引率
4.00%
发文量
102
审稿时长
33 days
期刊介绍: The European Journal of Integrative Medicine (EuJIM) considers manuscripts from a wide range of complementary and integrative health care disciplines, with a particular focus on whole systems approaches, public health, self management and traditional medical systems. The journal strives to connect conventional medicine and evidence based complementary medicine. We encourage submissions reporting research with relevance for integrative clinical practice and interprofessional education. EuJIM aims to be of interest to both conventional and integrative audiences, including healthcare practitioners, researchers, health care organisations, educationalists, and all those who seek objective and critical information on integrative medicine. To achieve this aim EuJIM provides an innovative international and interdisciplinary platform linking researchers and clinicians. The journal focuses primarily on original research articles including systematic reviews, randomized controlled trials, other clinical studies, qualitative, observational and epidemiological studies. In addition we welcome short reviews, opinion articles and contributions relating to health services and policy, health economics and psychology.
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