通过直接 RNA 测序揭示 C 到 U RNA 编辑事件

IF 3.6 3区生物学 Q2 BIOCHEMISTRY & MOLECULAR BIOLOGY RNA Biology Pub Date : 2023-12-13 DOI:10.1080/15476286.2023.2290843

Adriano Fonzino, Caterina Manzari, Paola Spadavecchia, Uday Munagala, Serena Torrini, Silvestro Conticello, Graziano Pesole, Ernesto Picardi

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引用次数: 0

摘要

在哺乳动物中，RNA 编辑事件包括 ADAR 酶将腺苷 (A) 转化为肌苷 (I)，或 APOBEC 酶家族将胞嘧啶 (C) 水解脱氨为尿嘧啶 (U)。

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Unraveling C-to-U RNA editing events from direct RNA sequencing

In mammals, RNA editing events involve the conversion of adenosine (A) in inosine (I) by ADAR enzymes or the hydrolytic deamination of cytosine (C) in uracil (U) by the APOBEC family of enzymes, mo...

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来源期刊

RNA Biology 生物-生化与分子生物学

CiteScore

8.60

自引率

0.00%

发文量

审稿时长

1 months

期刊介绍： RNA has played a central role in all cellular processes since the beginning of life: decoding the genome, regulating gene expression, mediating molecular interactions, catalyzing chemical reactions. RNA Biology, as a leading journal in the field, provides a platform for presenting and discussing cutting-edge RNA research. RNA Biology brings together a multidisciplinary community of scientists working in the areas of: Transcription and splicing Post-transcriptional regulation of gene expression Non-coding RNAs RNA localization Translation and catalysis by RNA Structural biology Bioinformatics RNA in disease and therapy