绘制澳大利亚小地区癌症风险因素流行图

IF 3 2区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH International Journal of Health Geographics Pub Date : 2023-12-19 DOI:10.1186/s12942-023-00352-5
James Hogg, Jessica Cameron, Susanna Cramb, Peter Baade, Kerrie Mengersen
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引用次数: 0

摘要

癌症是全球性的重大健康问题,众所周知,癌症风险因地域而异。然而,许多国家都没有高分辨率和完整覆盖范围的小地区级癌症风险因素数据,这阻碍了有针对性的预防策略的制定。以澳大利亚为例,研究人员利用 2017-2018 年全国健康调查为澳大利亚 2221 个小地区生成了流行率估计值,涉及吸烟、饮酒、体育锻炼、饮食和体重等八个癌症风险因素指标。利用最近开发的贝叶斯两阶段小地区估算方法,该模型纳入了仅用于调查的协变量、空间平滑和分层建模技术,以及大量小地区级辅助数据,包括人口普查、偏远地区和社会经济数据。这些模型借鉴了澳大利亚社会健康地图集之前公布的癌症风险估计值。估算结果经过了内部和外部验证。我们通过改进以前公布的癌症风险因素的覆盖范围和分辨率,说明 2017-2018 年澳大利亚各地的健康行为比以前认识到的表现出更大的空间差异。得出的估计结果显示,在较偏远地区和社会经济地位较低的地区,不健康行为的发生率较高;这一趋势与之前的工作十分吻合。我们的研究填补了澳大利亚小地区癌症风险因子估算的空白。新的估算结果提高了空间分辨率和覆盖范围,将使小区域癌症预防战略更有针对性。此外,通过将研究结果纳入目前提供小地区癌症发病率和相对生存率估算的澳大利亚癌症图谱的下一版本,这项工作将有助于决策者、研究人员和公众了解癌症风险因素的空间分布,从而更全面地了解澳大利亚的癌症情况。这项工作中应用的方法可推广到其他小区域估算应用中,并已证明在调查数据稀少的情况下也能很好地发挥作用。
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Mapping the prevalence of cancer risk factors at the small area level in Australia
Cancer is a significant health issue globally and it is well known that cancer risk varies geographically. However in many countries there are no small area-level data on cancer risk factors with high resolution and complete reach, which hinders the development of targeted prevention strategies. Using Australia as a case study, the 2017–2018 National Health Survey was used to generate prevalence estimates for 2221 small areas across Australia for eight cancer risk factor measures covering smoking, alcohol, physical activity, diet and weight. Utilising a recently developed Bayesian two-stage small area estimation methodology, the model incorporated survey-only covariates, spatial smoothing and hierarchical modelling techniques, along with a vast array of small area-level auxiliary data, including census, remoteness, and socioeconomic data. The models borrowed strength from previously published cancer risk estimates provided by the Social Health Atlases of Australia. Estimates were internally and externally validated. We illustrated that in 2017–2018 health behaviours across Australia exhibited more spatial disparities than previously realised by improving the reach and resolution of formerly published cancer risk factors. The derived estimates revealed higher prevalence of unhealthy behaviours in more remote areas, and areas of lower socioeconomic status; a trend that aligned well with previous work. Our study addresses the gaps in small area level cancer risk factor estimates in Australia. The new estimates provide improved spatial resolution and reach and will enable more targeted cancer prevention strategies at the small area level. Furthermore, by including the results in the next release of the Australian Cancer Atlas, which currently provides small area level estimates of cancer incidence and relative survival, this work will help to provide a more comprehensive picture of cancer in Australia by supporting policy makers, researchers, and the general public in understanding the spatial distribution of cancer risk factors. The methodology applied in this work is generalisable to other small area estimation applications and has been shown to perform well when the survey data are sparse.
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来源期刊
International Journal of Health Geographics
International Journal of Health Geographics PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH -
CiteScore
10.20
自引率
2.00%
发文量
17
审稿时长
12 weeks
期刊介绍: A leader among the field, International Journal of Health Geographics is an interdisciplinary, open access journal publishing internationally significant studies of geospatial information systems and science applications in health and healthcare. With an exceptional author satisfaction rate and a quick time to first decision, the journal caters to readers across an array of healthcare disciplines globally. International Journal of Health Geographics welcomes novel studies in the health and healthcare context spanning from spatial data infrastructure and Web geospatial interoperability research, to research into real-time Geographic Information Systems (GIS)-enabled surveillance services, remote sensing applications, spatial epidemiology, spatio-temporal statistics, internet GIS and cyberspace mapping, participatory GIS and citizen sensing, geospatial big data, healthy smart cities and regions, and geospatial Internet of Things and blockchain.
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