经济实惠的实验室规模电纺丝装置,配有可互换的收集器,可实现有针对性的纤维形成

IF 2 Q3 ENGINEERING, ELECTRICAL & ELECTRONIC HardwareX Pub Date : 2023-12-12 DOI:10.1016/j.ohx.2023.e00501
Alexi Switz , Aditi Mishra , Katrina Jabech , Anamika Prasad
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引用次数: 0

摘要

由于电纺丝法能够生产纳米到微米范围的纤维,其应用领域包括生物医学、过滤、储能和传感等多个方面,因此需求量越来越大。其中许多应用都需要控制纤维的布局和直径。然而,标准平板收集器产生的纤维是随机的,对直径和密度的控制有限。能提供更高水平控制的其他可行解决方案要么数量稀少,要么价格昂贵,阻碍了这一重要技术的普及。本研究通过设计一种经济实惠的实验室规模电纺丝装置来应对这一挑战,该装置配备了可互换的收集器,可生成随机、对齐和盘绕的目标纤维。收集器包括标准平板和另外两种设计,即旋转鼓和喷丝板尖端收集器。旋转鼓式收集器具有可调速度控制功能,可收集排列整齐的纤维,即使在高速旋转时也能保持稳定。喷丝头收集器的设计目的是生产螺旋卷绕的纤维。该装置通过使用聚己内酯(PCL)(一种可生物降解且经 FDA 批准的聚合物)进行定向纤维形成进行了验证。总之,该设计的独特之处在于其经济性、可修改性和使用现成材料的可复制性,从而扩大了电纺丝技术的应用范围。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Affordable lab-scale electrospinning setup with interchangeable collectors for targeted fiber formation

The electrospinning method is increasingly in demand due to its capability to produce fibers in the nanometer to micrometer range, with applications in diverse fields including biomedical, filtration, energy storage, and sensing. Many of these applications demand control over fiber layout and diameter. However, a standard flat plate collector yields random fibers with limited control over diameter and density. Other viable solutions offering a higher level of control are either scarce or substantially expensive, impeding the accessibility of this vital technique. This study addresses the challenge by designing an affordable laboratory-scale electrospinning setup with interchangeable collectors, enabling the creation of targeted fibers from random, aligned, and coiled. The collectors include the standard flat plate and two additional designs, which are a rotating drum and a spinneret tip collector. The rotating drum collector has adjustable speed control to collect aligned fibers and exhibits stability even at high rotational speeds. The spinneret tip collector was designed to produce helically coiled fibers. The setup was validated by directed fiber formation using polycaprolactone (PCL), a biodegradable and FDA-approved polymer. Overall, the uniqueness of the design lies in its affordability, modifiability, and replicability using readily available materials, thus extending the reach of the electrospinning technique.

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来源期刊
HardwareX
HardwareX Engineering-Industrial and Manufacturing Engineering
CiteScore
4.10
自引率
18.20%
发文量
124
审稿时长
24 weeks
期刊介绍: HardwareX is an open access journal established to promote free and open source designing, building and customizing of scientific infrastructure (hardware). HardwareX aims to recognize researchers for the time and effort in developing scientific infrastructure while providing end-users with sufficient information to replicate and validate the advances presented. HardwareX is open to input from all scientific, technological and medical disciplines. Scientific infrastructure will be interpreted in the broadest sense. Including hardware modifications to existing infrastructure, sensors and tools that perform measurements and other functions outside of the traditional lab setting (such as wearables, air/water quality sensors, and low cost alternatives to existing tools), and the creation of wholly new tools for either standard or novel laboratory tasks. Authors are encouraged to submit hardware developments that address all aspects of science, not only the final measurement, for example, enhancements in sample preparation and handling, user safety, and quality control. The use of distributed digital manufacturing strategies (e.g. 3-D printing) is encouraged. All designs must be submitted under an open hardware license.
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