[一种新的黄酮醇苷,来自白花蛇舌草)。

Q3 Pharmacology, Toxicology and Pharmaceutics Acta pharmaceutica Sinica Pub Date : 2008-10-01
Wen-jie Lu, Qi-kang Ya, Jia-yuan Chen, Bu-ming Liu
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引用次数: 0

摘要

为了研究传统中草药白花蛇舌草(Baeckea Frutescens L.)的化学成分、一种名为 6,8-二甲基堪非醇-3-O-alpha-L-鼠李糖苷(1)的新黄酮醇苷,以及七种已知化合物:通过硅胶柱色谱法、聚酰胺柱色谱法和重结晶法,分离出了名为 6,8-二甲基堪非醇-3-O-alpha-L-鼠李糖苷(1)的新黄酮醇苷,以及七种已知化合物:槲皮素(2)、槲皮素-3-O-alpha-L-鼠李糖苷(3)、杨梅素(4)、杨梅素-3-O-alpha-L-鼠李糖苷(5)、没食子酸(6)、熊果酸(7)和 1,3-二羟基-2-(2'-甲氧基丙酰基)-5-甲氧基-6-甲基苯(8)。根据理化性质和光谱分析确定了它们的结构。其中,化合物 2-7 是首次从该植物中分离出来,化合物 8 是首次从该植物中分离出来。
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[A new flavonol glycoside from Baeckea Frutescens L].

To study the chemical constituents of the traditional Chinese herb Baeckea Frutescens L., a new flavonol glycoside, named 6, 8-dimethylkaempferol-3-O-alpha-L-rhamnoside (1), together with seven known compounds: quercetin (2), quercetin-3-O-alpha-L-rhamnoside (3), myricetin (4), myricetin-3-O-alpha-L-rhamnoside (5), gallic acid (6), ursolic acid (7) and 1,3-dihydroxy-2-(2'-methoxylpropionyl)-5-methoxy-6-methylbenzene (8) were isolated by using silica gel column chromatography, polyamide column chromatography and recrytallization. Their structures were identified on the basis of physicochemical properties and spectroscopic analysis. Among them, compounds 2-7 were isolated from this plant for the first time and compound 8 was first isolated from plant.

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