多发性骨髓瘤:融合社区和学术护理的范例。

IF 2.9 3区 教育学 Q1 EDUCATION, SCIENTIFIC DISCIPLINES Hematology. American Society of Hematology. Education Program Pub Date : 2023-12-08 DOI:10.1182/hematology.2023000431
Jesús G Berdeja
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引用次数: 0

摘要

多发性骨髓瘤(MM)患者的治疗非常复杂,大多数患者需要在数年至数十年的时间里接受多线治疗。自体干细胞移植成为一大部分患者的标准治疗方法以来,社区诊所和专业学术中心必须通力合作,优化患者的初始治疗。现在,随着治疗选择的空前增多,以及嵌合抗原受体T细胞疗法和双特异性T细胞激活剂的引入,这种合作变得更加重要,并从前期治疗延伸到复发和难治性疾病的治疗。我将讨论独特的安全性和后勤方面的问题,这些问题为安全、成功地提供这些疗法带来了挑战和机遇。肿瘤初诊医生、骨髓瘤专科医生和移植或免疫效应细胞提供者之间需要密切互动、沟通和建立合作关系,以便为每位患者提供最佳的纵向治疗。这种治疗骨髓瘤的多学科方法可以作为融合社区和学术护理的范例。
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Multiple myeloma: a paradigm for blending community and academic care.

The care of the multiple myeloma (MM) patient is complex, with most patients requiring multiple lines of therapy over a span of many years to decades. Since the days when autologous stem cell transplantation became the standard of care for a large subset of patients, it was imperative that community practices and specialized academic centers work together to optimize the initial care of patients. Now, with the unprecedented number of treatment options and the introduction of chimeric antigen receptor T-cell therapies and bispecific T-cell engagers, that collaboration has become even more important and stretches from the upfront treatment to the relapsed and refractory disease setting. I will discuss the unique safety profile and logistical aspects that pose challenges and opportunities for the safe and successful delivery of these therapies. Close interaction, communication, and established partnerships between the primary oncologist, the myeloma specialist, and the transplant or immune effector cell provider will be required to provide the optimal care longitudinally for each patient. This multidisciplinary approach to treating MM can serve as a paradigm for blending community and academic care.

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来源期刊
Hematology. American Society of Hematology. Education Program
Hematology. American Society of Hematology. Education Program EDUCATION, SCIENTIFIC DISCIPLINES-HEMATOLOGY
CiteScore
4.70
自引率
3.30%
发文量
0
期刊介绍: Hematology, the ASH Education Program, is published annually by the American Society of Hematology (ASH) in one volume per year.
期刊最新文献
Atypical CML: diagnosis and treatment. Langerhans cell histiocytosis: promises and caveats of targeted therapies in high-risk and CNS disease. Multiple myeloma: a paradigm for blending community and academic care. The sum of the parts: what we can and cannot learn from comorbidity scores in allogeneic transplantation. Thrombopoietin receptor agonists for chemotherapy-induced thrombocytopenia: a new solution for an old problem.
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