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摘要

重度抑郁症(MDD)的发病率很高,其特征往往是使人衰弱的行为和认知症状。人们对 MDD 的了解甚少,这很可能是由于它具有相当大的异质性和自我报告驱动的症状表现。虽然研究人员一直在探索机器学习筛查 MDD 的能力,但对个别症状的关注却少得多。我们认为,了解客观数据流与个体抑郁症状之间的关系对于理解 MDD 的显著异质性非常重要。因此,我们开展了一项综合比较研究,探索机器学习预测九种自我报告的抑郁症状与通话和文本日志的能力。我们从 300 多名参与者的日志中创建了时间序列,每 4、6、12 或 24 小时汇总一次通信属性(平均长度、次数或联系人)。我们最成功地预测了行动异常,平衡准确率为 0.70。此外,我们预测自杀意念的平衡准确率为 0.67。事实证明,发送短信是最有用的日志类型。这项研究为未来旨在对 MDD 进行个性化评估和干预的移动健康研究提供了宝贵的见解。
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Mobile Communication Log Time Series to Detect Depressive Symptoms.

Major Depressive Disorder (MDD) is highly prevalent and characterized by often debilitating behavioral and cognitive symptoms. MDD is poorly understood, likely due to considerable heterogeneity and self-report-driven symptomatology. While researchers have been exploring the ability of machine learning to screen for MDD, much less attention has been paid to individual symptoms. We posit that understanding the relationship between objective data streams and individual depression symptoms is important for understanding the considerable heterogeneity in MDD. Thus, we conduct a comprehensive comparative study to explore the ability of machine learning to predict nine self-reported depressive symptoms with call and text logs. We created time series from the logs of over 300 participants by aggregating communication attributes- average length, count, or contacts- every 4, 6, 12, or 24 hours. We were most successful predicting movement irregularities with a balanced accuracy of 0.70. Further, we predicted suicidal ideation with a balanced accuracy of 0.67. Outgoing texts proved to be the most useful log type. This study provides valuable insights for future mobile health research aimed at personalizing assessment and intervention for MDD.

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